Association of Plasma Level of Thiobarbituric Acid Reactive Substances with Extent of Hepatocellular Injury in Preterm Infants with Cholestatic Jaundice
Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 2
Abstract
The present study was designed to determine the association between extent of hepatocellular injury and plasma level of thiobarbituric acid reactive substances (TBARS) in pre term infants with cholestasis. Preterm infants (2 mg/dl) (n = 25) or in the control group (n = 16). Blood samples for measurement of TBARS, direct bilirubin and transaminases were obtained with-in 24 hours of enrollment. The cholestasis and control groups were comparable with respect to gestational age, birth weight and Apgar score. Serum direct bilirubin, SGOT (EC 2.6.1.1) and SGPT (EC 2.6.1.2) levels were significantly high in the cholestasis group. Plasma levels of TBARS in cholestasis group were correlated with SGOT (F=276.92; P
Authors and Affiliations
M Maneesh, Bhumika Upadhya, R Bhutia
Keywords
Related Articles
- EP ID EP101992
- DOI -
- Views 79
- Downloads 0
SERUM ALPHA-2-MACROGLOBULIN, ANTITRYPSIN AND ANTICHYMOTRYPSIN ACTIVITIES IN PATIENTS RECEIVING TREATMENT WITH CYCLOSPORINE
Cyclosporine has been reported to function as an inhibitor of the chymotrypsin like activity of proteasome. We hypothesized that the administration of an exogenous proteinase inhibitor may affect the activities of the...
STUDIES OF BIOCHEMICAL PARAMETERS IN BREAST CANCER WITH AND WITHOUT<br /> METASTASIS
The study includes 102 confirmed cases of carcinoma breast with and without metastasis and 25 healthy non-pregnant females. They were evaluated for blood levels of Ferritin, GSH, LDH, ALP, GGT and Hb before and 21 days...
EFFECT OF INCREASING DURATION OF DIABETES MELLITUS TYPE 2 ON GLYCATED HEMOGLOBIN AND INSULIN SENSITIVITY
Non-insulin dependent diabetes mellitus (NIDDM) is the most rapidly growing chronic metabolic disorder in the world. With advancement in the age and duration of diabetes there is a gradual tendency for the level of blo...
DEPLETED NITRITE AND ENHANCED OXIDATIVE STRESS IN UROLITHIASIS
Crystal aggregation and retention are critical events for the formation of kidney stones. There is a close association between crystal development and free radical activity in vivo. In the present study 30 subjects pre...
Isolation and Culture of Leydig Cells from Adult Rats