Association of Plasma Level of Thiobarbituric Acid Reactive Substances with Extent of Hepatocellular Injury in Preterm Infants with Cholestatic Jaundice
Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 2
Abstract
The present study was designed to determine the association between extent of hepatocellular injury and plasma level of thiobarbituric acid reactive substances (TBARS) in pre term infants with cholestasis. Preterm infants (2 mg/dl) (n = 25) or in the control group (n = 16). Blood samples for measurement of TBARS, direct bilirubin and transaminases were obtained with-in 24 hours of enrollment. The cholestasis and control groups were comparable with respect to gestational age, birth weight and Apgar score. Serum direct bilirubin, SGOT (EC 2.6.1.1) and SGPT (EC 2.6.1.2) levels were significantly high in the cholestasis group. Plasma levels of TBARS in cholestasis group were correlated with SGOT (F=276.92; P
Authors and Affiliations
M Maneesh, Bhumika Upadhya, R Bhutia
Keywords
Related Articles
- EP ID EP101992
- DOI -
- Views 64
- Downloads 0
ESTIMATION OF mRNA LEVELS OF INTERLEUKIN (IL) -10, TUMOR NECROSIS FACTOR (TNF) - α, IL - 4 AND INTERFERON (IFN) - γ IN HIV INFECTED CHILDREN IN MUMBAI
Cytokines, viral load and opportunistic infections play an important role in HIV-disease progression. Hundred children vertically infected with HIV were enrolled to determine mRNA levels of TNF-α, IL-10, IL-4 and IFN -...
SERUM LIPIDS AND MALONDIALDEHYDE LEVELS IN PRIMIPAROUS PATIENTS WITH PREGNANCY INDUCED HYPERTENSION
BACKGROUND : Pregnancy induced hypertension (PIH) contributes to 15.6% maternal mortality in India. In Behrampur, Orissa, maternal deaths due to PIH was 32%, which is twice the national incidence. Hence in this populat...
PLACE OF SALIVARY ß GLUCURONIDASE ACTIVITY IN HEAD & NECK CANCERS
Salivary ß-glucuronidase activity was studied in 20 healthy subjects without habits and 10 with habits, 38 untreated patients of advanced head and neck cancer and 21 patients after treatment either after surgery or rad...
ANTIOXIDANT STATUS IN NEONATAL JAUNDICE BEFORE AND AFTER PHOTOTHERAPY
Phototherapy has been related to increased oxidative stress and lipid peroxidation. In the present study, thirty full term jaundiced neonates with appropriate weight were analyzed before and after completion of phototh...
CHORONIC EFFECTS OF LAMOTRIGINE ON LIVER FUNCTION IN ADULT MALE RATS
A number of newly developed antiepileptic drugs are currently in use, among them Lamotrigine (LTG) is more common. Despite the extensive use of this drug, it has not been possible to predict the side effects especially...