Association of Serum Homocysteine Levels in Stroke Patient With Ct Scan Findings
Journal Title: IJAR-Indian Journal of Applied Research - Year 2016, Vol 6, Issue 8
Abstract
Introduction : The burden of stroke comprises largely of the elderly population. However, there remains a small but significant subset of younger patients with ischemic stroke, in whom conventional vascular risk factors play a smaller role. Hyperhomocysteinemia causes increased arterial blood pressure thereby increasing the risk of cerebrovascular accidents. Neuroimaging plays a vital role in the workup of acute stroke by providing information essential to accurately triage patients, expedite clinical decision making with regards to treatment, and improve outcomes in patients presenting with acute stroke. So the aim of the study is to study serum homocysteine levels to assess it's role as a risk factor for stroke with CT scan finding. Materials and Methods : 40 patients of cerebrovascular accidents admitted . The study was carried out in patients admitted with focal neurological deficit Serum homocysteine was estimated by enzymatic photometry method. CT scan was done for each patient. Results : It was found that the serum homocysteine levels were slightly higher in patients with recurrent stroke than new cases of stroke, Mean serum homocysteine levels were higher in patients with infarct than in patients with normal CT finding Mean serum homocysteine levels were higher in patients with hemorrhage than in patients with normal CT finding. Mean serum homocysteine levels were higher in patients with hemorrhage and infarct taken together than in patients with normal CT finding.Conclusion: CT allows time-critical decision-making in stroke patients, informing decisions on thrombolytic therapy with tPA, which has a narrow therapeutic index.People at risk for cerebrovascular diseases such as hypertension, smoking and sedentary lifestyle should be screened for hyperhomocysteinemia. In conclusion the present study revealed that hyperhomocysteinemia appears to be an important risk factor for cerebrovascular accidents.
Authors and Affiliations
Dr. Raghav Jayaseelan, Dr. Syed Hafeezullah
Keywords
Related Articles
- EP ID EP363063
- DOI -
- Views 55
- Downloads 0
ESTIMATION OF FETAL WEIGHT WITH VARIOUS METHODS AND ITS CORRELATION WITH BIRTH WEIGHT
Objective: This study was to estimate the fetal weight in term pregnancy by clinical methods and ultrasound and to compare the results with actual birth weight (ABW). Material and Methods: This study was conducted at a t...
Analysis of Money Supply in India during 2009-10 to 2013-14
Money supply plays an important role in terms of affecting the national income, prices, trade etc. Th-ere fore, regulation of required changes in money supply is pre requisite for the smooth functioning of the economy. I...
EVALUATION OF HISTOPATHOLOGICAL CORRELATION WITH ALVARADO SCORE IN ACUTE APPENDICITIS
Background: Acute appendicitis is one of the most frequent abdominal emergencies, and cannot be diagnosed with 100% accuracy in early stage. Various laboratory and imaging investigations though helpful are not 100% diagn...
A STUDY OF SERUM CK-MB LEVEL IN NON DIALYSED CHRONIC KIDNEY DISEASE PATIENTS
Chronic kidney disease is associated with early increased risk of cardiovascular morbidity and mortality. CK-MB the traditional marker for myocardial ischemia loses its specifity in renal failure because of non cardiac s...
A Study of Post Operative Wound Infection After Laparotomies: our Experience
Aims And Objectives: To determine the incidence and types of surgical site infections following laparotomies, to study the risk factors in patients who developed SSI and to study the causative organisms and their sensiti...