Association of Serum Magnesium Level with Major Risk Factor, Thrombolysis and Echocardiography in Patients with Acute Coronary Syndrome
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 3
Abstract
Megnesium depletion plays a key role in the pathphysiologic features of diabetes mellitus, hypertension, thrombosis, arrhythmias and coronary artery disease. Whether the depletion is related to the Echocardiographic parameters in an acute phase of acute coronary syndrome is not known. The objective of the study is to explore the status of serum magnesium in acute coronary syndrome patients. To investigated the association of serum magnesium levels with major risk factor, fibrinolysis and echocardiography in Patients with acute coronary syndrome. The 68 patients with were divided into three groups: STEMI, NSTEMI and unstable angina. The 24 healthy individuals matched as a control group. Serum Mg was measured in all patients groups and control group, the analysis is performed in an atomic absorption spectrophotometer (Schmiadzu AA5646). Estimation of serum glucose, urea, creatinine, lipid profile was done by colorimetric method. The mean ±SD value of serum Mg levels in patients with ACS was significantly lower than those in normal controls. ANOVA test revealed there was non significant difference in the value of serum Mg mean ±SD levels among three types of acute coronary syndrome, t- test revealed there was non significant difference in the value of serum Mg mean±SD levels in the presence or absente of diabetes millitus, Dyslipidemia, Hypertension, Smoking, Obesity and fibrinolytic treatment. The mean (±SD) value of serum Mg levels was non-significantly associated with mitral regurgitataion (MR) severity and diastolic dysfunction stages. There was non-significant correlation between the serum Mg concentration and the value of Isovolumic relaxation time, E (left ventricular inflow velocity) / e (tissue doppler velocity) ratio and Decceleration time, Age, Diameter of left atrium and Left Ventricular Ejection Fraction (LVEF). Decreases Serum magnesium level indicate ischemia severity in acute coronary syndrome patients, Serum magnesium level non significantly associated with major risk factor, fibrinolytic treatment and Echocardiographic parameter in acute phase of disease.
Authors and Affiliations
Dr. Wafa Mansor Merza
Keywords
Related Articles
- EP ID EP197192
- DOI -
- Views 67
- Downloads 0
Medicinal plants with antidiabetic activity - A review of herbal medicine
Diabetes mellitus is one of the most common non-communicable diseases globally. It is the fourth leading causes of death in the most developed countries and there in substantial evendiced that it in epidemic in many deve...
Recent trends in microencapsulation: A review
Microcapsules are tiny capsules containing materials (such as adhesive or a medicine) that are released when the capsule is broken, melted or dissolved. The process of forming microcapsules is called microencapsulation....
Epidemiological study of blood pressure in school children (5-14 years) in Kadapa
Background measurement of blood pressure is not routinely employed in our country in various health checkup programs and studies pertaining to BP of school going children are inadequate and do not have any percentile cha...
Prevalence of metallo-β-lactamases in clinical isolates of Pseudomonas aeruginosa from King Abdulaziz University Hospital in Jeddah
Pseudomonas aeruginosa is an opportunistic pathogen associated with a wide range of nosocomial infections. A total of 75 P. aeruginosa clinical isolates were obtained from microbiology lab at King Abdulaziz University Ho...
Exploration of cytotoxic and antioxidant potential of Antigonon leptopus (Family: Polygonaceae)
Antigonon leptopus leaf extracts were explored for their phytochemical, antioxidant and cytotoxic activity. Four solvent extracts namely hexane, chloroform, ethyl acetate and methanol extracts were prepared. All extracts...