Association rules analysis of Fufang Kushen injection in combination with traditional Chinese medicine or modern medications in treating Cervical cancer: real-world retrospective study
Journal Title: Medical Data Mining - Year 2018, Vol 1, Issue 1
Abstract
Objective: The present study aimed to analyze the association rules of Fufang Kushen injection in combination with other traditional Chinese medicine (TCM) or modern medications in treating cervical cancer (CC) based on the electrical medical records extracted from real-world hospital information system. Methods: The clinicians’ prescriptions regarding to the combination of with TCM or modern medications were from hospital information system electronic medical data integration warehouse established by the Institute of Basic Medical Research of Chinese Medicine, China Academy of Chinese Medical Sciences, which integrated the hospital information system data of 22 hospitals. The association rules of the drug characteristics were analyzed through Apriori algorithm. Results: A total of 839 patients with CC were included. We found that is often combined with prescriptions which could clear heat, remove toxicity, supplement Qi. also combined with chemotherapeutic drugs, immunomodulatory drugs, 5-HT receptor blockers, and glucocorticoids. The combination presents a specific law. Conclusion: Fufang Kushen injection combined with hepatoprotective drugs, immunomodulators and glucocorticoids is often used to treat cervical cancer.
Authors and Affiliations
Fu-Mei Liu1, Yan-Ming Xie1, Yin Zhang1*, Cen Chen2, Chang Zhang2, Yan Zhuang3
Keywords
Related Articles
- EP ID EP710365
- DOI -
- Views 33
- Downloads 0
Efficacy and safety of atomized inhalation for Shuanghuanglian on chronic pharyngitis:a Meta-analysis of the randomized controlled trials
Objective: As a Chinese drugs preparation to clear heat and remove toxicity, Shuanghuanglian (SHL) has been widely used, but the clinical efficacy and safety of SHL on chronic pharyngitis remain unclear, especially the a...
Effects of Written Emotional Disclosure on Burden, Trauma Symptoms and Health Status in Primary Caregivers of The Patient: A meta-analysis
Objective: The meta-analysis aims to evaluate the efficacy of written emotional disclosure on burden, trauma symptoms and health status in primary caregivers of the patient. Methods: Randomized controlled trials (RCTs) o...
Clinical Medicine Characteristics Study of Traditional Chinese Medicine in the treatment of cancer pain based on Data Mining
Objective: To explore the clinical characteristics of traditional Chinese medicine in the treatment of cancer pain based on traditional Chinese medicine inheritance support system (TCMISS). Methods: China Chinese CNKI da...
The research progress of acupuncture and moxibustion in the treatment of peripheral facial paralysis
As a common and frequently-occurring disease in clinic, peripheral facial paralysis is worth paying attention to. In fact, as one of the methods for the treatment of peripheral facial paralysis, acupuncture has been wide...
Unsatisfied methodological qualities assessment of systematic reviews/Meta-analyses on Chinese medicine for stroke and their risk factors
Background: Stroke is not only high in morbidity and mortality but also poses a great burden of disease and it is also the most reported disease in Chinese medicine systematic reviews. Therefore, the quality of such evid...