Atropine induced psychosis: a consequence during the organophosphate poisoning treatment
Journal Title: Indian Journal of Basic and Applied Medical Research - Year 2018, Vol 7, Issue 2
Abstract
Atropine is a known and an established antidote in organophosphorus poisonings and it also helps to improve the extrapyramidal symptoms as it can cross the blood brain barrier. In the literature, the reports of atropine intoxication is not rare. Nevertheless, the reports of atropine abuse leading to psychosis are infrequent. Here, we present the case of 39 year old male patient who received atropine as part of antidote therapy for Organophosphorus poisoning and the drug was within the recommended dose. After the drug was administered, the patient developed restlessness, delirium, hallucinations, irrelevant talk along with tachycardia and dilated pupils not reacting to light suggesting possible 'anti-cholinergic abuse'. The patient was managed by titrating down the atropine's dose and administration of haloperidol and promethazine.
Authors and Affiliations
Madiha Nooreen
Keywords
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