Attenuation of Hemodynamic Responses to Laryngoscope and End tracheal Intubation, Role of I.V Bolus Dose of Esmolol Hydrochloride and Lignocaine Hydrochloride - a Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Introduction: There is substantial evidence that laryngoscopy and endotracheal intubation in lightly anesthetized patients are accompanied by a significant increase in heart rate and arterial blood pressure . These changes are usually short duration and well tolerated by patients in the absence of cardiovascular diseases or disturbed intracranial pressure homeostasis.Various strategies have been applied to attenuate these responses. These include minimizing the duration of laryngoscopy to less than 15 seconds, use of I.V or topical lidocaine, deep inhalational anesthetics, I.V. Narcotics, adrenoceptor blocking agents, vasodilators, calcium channel blockers, intranasal nitroglycerin spray and ointment, Ganglion blockers. AIMS & OBJECTIVES: 1.To compare the efficacy of intravenous bolus dose of Esmolol Hydrochloride versus Lignocaine Hydrochloride to attenuate the hemodynamic responses during general anaesthesia requiring laryngoscopy and endotracheal intubation. 2.To compare the heart rate and systolic, diastolic and mean arterial blood pressures. CONCLUSION: This study shows the intravenous bolus dose of esmolol hydrochloride 0.5 mg per kg body weight is superior to intravenous lignocaine hydrochloride 1.5 mg per kg body weight IV bolus to attenuate the hemodynamic responses to Laryngoscopy and endotracheal intubation.
Authors and Affiliations
Dr. N. Syama Kumar, Dr. K. Nagabhushanam, Dr. G. G. N. Sudharani, Dr. S. Seetharamaiah
Keywords
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- EP ID EP376616
- DOI 10.9790/0853-1706095157.
- Views 64
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