Bacteriological Profile ofBlood Culture Positive Sepsis inNeonatesin A Tertiary Care Centre.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 4
Abstract
This prospective study was conducted in SNCU of GMCH to find out the bacteriological profile of neonatal sepsis and their sensitivity. In 93(13.64%) neonates out of 682 neonates, organisms were isolated. 56(60.22%) neonates had early onset sepsis and 37(39.78%) neonates had late onset sepsis. CoNS was the commonest organism causing both early (in 48.21%) and late ( in 54.05%) onset sepsis respectively, followed by E. coli in EOS and Klebsiella species in LOS. 48.80% and 27.66% of CoNS were sensitive to linezolid and vancomycin respectively. All (100%) S. aureus were sensitive to vancomycin and linezolid, 80% were sensitive to ciprofloxacin and 60% were sensitive to gentamycin and amikacin. 40% of Klebsiella sp were sensitive to vancomycin and ciprofloxacin. 54.54% and 27.27% of E. coli were sensitive to vancomycin and ciprofloxacin respectively. 60 % of gram negative bacilli were sensitive to vancomycin. 60% of S. aureus were resistant to ceftriaxone/cefotaxime and penicillin. 25% of Klebsiella sp. were resistant to pipercillin and tazobactum. 36.36% of E. coli were resistant to ciprofloxacin, amikacin, ceftriaxone/cefotaxime and pipercillin tazobactum combination. 66.66% Pseudomonas sp. showed resistance to vancomycin and 33.33% showed resistance to pipercillin and tazobactum.
Authors and Affiliations
Dr Indira Das, Dr Kumud Pathak, Dr Akher Ali, Dr Mahibur Rahman, Dr Ashok Singh, Dr Nishant Kumar
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