Attenuation of pressor response to laryngoscopy and intubation: A comparative study of efficacy of topical nitroglycerine, sublingual nifedipine and intravenous lignocaine
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 9
Abstract
Background: Laryngoscopy and tracheal intubation frequently induce a cardiovascular stress response and may cause profound alteration of the hemodynamic state as consequences of anesthetic drug effects. A lot of methods have been tried to attenuate the cardiovascular response to laryngoscopy and intubation. Material and Methods: Study was carried on 100 patients aged between 20 to 60 years and randomly divided into 4 groups of 25 each as Group I (Control group), Group II (nitroglycerine 2% topically), Group III (nifedipine sublingually), Group IV (2% xylocaine intravenously) prior to intubation. Pulse rate, systolic and diastolic blood pressure were recorded at different time intervals. Results: The highest increase in pulse rate was in control Group I and less increase in lignocaine Group IV. Comparison of control Group I with Nitroglycerine Group II, Nifedipine Group III, Lignocaine Group IV there was statistically highly significant difference in the changes in mean systolic blood pressure at all the time intervals. Discussion: Intravenous lignocaine was more effective in attenuating the pulse rate and rate pressure product response to laryngoscopy and intubation, while topical nitroglycerine was best in attenuating the blood pressure.
Authors and Affiliations
Ravindra B Jalkote, Varsha Keshavrao Warke
Keywords
Related Articles
- EP ID EP268622
- DOI -
- Views 70
- Downloads 0
Effectiveness of propofol in day care short surgical procedures – A hospital based longitudinal study
Present study was conducted to study the use of Propofol as a total intravenous anaesthetic agent in short surgical day care procedures. A hospital based longitudinal study was conducted with total 50 patients in the dep...
Thrombocytosis as a Significant Indicator of Prognosis of Renal Cell Carcinoma
Background: Various prognostic factors have been studied to predict the survival of renal cell carcinoma (RCC) during last decades. In many types of malignancies, thrombocytosis has been reported and studied as a prognos...
Clinicopathologic study of pediatric neoplasm
Objective: Paediatric malignancies, being a significant cause of death among children. This study was performed with an aim to find out the profile of childhood cancers in rural tertiary care hospital, for a period of si...
Pattern of acute coronary syndrome presentation in women
Introduction: Cardiovascular disease (CVD) constitutes the leading cause of death for women in developed countries. It is a more common cause of death than cancer and leads to one death every minute. Results of our study...
Malignant Sacrococcygeal Teratoma with Yolk Sac Tumor – Rare Case Report
Abstract: Malignant sacrococcygeal Yolk sac tumor is an extremely rare extra-gonadal germ cell tumor. Hereby presenting a case of 1 year female child presenting with the history of swelling at lumbosacral region since bi...