Auditory and Visual Reaction Time in Polycystic Ovarian Syndrome
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 6
Abstract
ABSTRACT Introduction: Polycystic Ovarian Syndrome (PCOS) is a hormonal disorder of female reproductive system causing infertility, irregular menstrual cycle and hormonal imbalance characterised by hyperestrogenemia, hyperprolactinemia, increased Anti Mullerian Hormone (AMH) and Thyroid Stimulating Hormone (TSH). Apart from the role in female reproductive system, these hormones are shown to have neuromodulatory role, affecting the neuronal activity. Thus, the auditory and visual reaction time may be affected in the women with polycystic ovaries. Aim: To evaluate the auditory and visual reaction time, in patients with polycystic ovarian syndrome. Materials and Methods: The study was designed as a case-control study where the 80 otherwise healthy women, attending infertility OPD, were recruited for the study and divided into groups viz., PCOS (n=40) and NPCOS (n=40). The subjects from both the groups were evaluated for their anthropometric data, hormone levels {Serum estrogen, Serum prolactin, Serum TSH, Serum AMH} using COBAS-6000 analyser along with the auditory and visual reaction time using RTM-608 (Medicaid). The observations were recorded and analysed using paired t-test. Results: Auditory reaction time had significantly decreased (p=0.012) while visual reaction time was non-significantly reduced in Group PCOS as compared to Group NPCOS. Conclusion: The altered hormonal profile in PCOS i.e., hyperestrogenemia and hyperprolactinemia exerts enhanced neuromodulatory action through neural ERĪ± receptors and tuberoinfundibular dopaminergic neurons in hypothalamus, thus resulting in increased neuronal excitability and decreased reaction time in patients with PCOS.
Authors and Affiliations
Rupali Mehta, Manjinder Kaur, Pooja Gandhi, Priyanka Parihar
Keywords
Related Articles
- EP ID EP522532
- DOI 10.7860/JCDR/2018/31863.11646
- Views 75
- Downloads 0
Evaluation of Liver Stiffness in Healthy Individuals by Sonoelastography
Introduction: Successfully detecting and managing Liver Fibrosis (LF) at an early phase can significantly improve the prognosis of patients in clinical practice; therefore, accurately assessing the degree of fibrosis whe...
An Unusual Case of Giant ArterioVenous Malformation of Anterior Abdominal Wall
Arterio-Venous Malformations (AVMs) are high flow vascular anomalies, commonly seen in head, neck and extremities. AVMs represent a direct connection between the arterial and the venous systems. They are congenital, ofte...
Primary Intraventricular Haemorrhage: Clinical and Aetiological Profile with Predictors of Outcome-A Hospital Based Study
ABSTRACT Introduction: Primary Intraventricular Haemorrhage (PIVH) is defined as bleeding in the ventricular system without a discernable parenchymal component or arising within 15 mm from the ventricular wall. PIVH is r...
Oncogenic Human Papillomavirus Genotypes and Cervical Cancer: A Focus on Multiple Infections and Patient Age
ABSTRACT Introduction: Cervical cancer is the leading cause of cancer-related deaths in the female population. Human Papillomavirus (HPV) genotypes 16 and 18 accounts for 70% of cervical cancer cases. HPV infection is as...
Financial Burden of Out-of-Pocket Expenditures for Primary Health Care in Hilly Areas of Garhwal Region, Uttarakhand, North India
Introduction: High total health expenditures via Out-of-Pocket (OOP) as formal user fees and informal payments put India in challenging situation to achieve towards universal health coverage. Aim: To assess the (OOP) exp...