Bacteria Patterns in Infected Diabetic Foot: Is There A Surgical Implication?
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 10
Abstract
<strong>Background: </strong>The number of patients suffering from diabetes and its complications in the world is doubling every 10-15 years. Apart from development of retinopathy, nephropathy, and diabetic-induced atherosclerotic changes in high caliber arteries. Critical ischemia with gangrenous changes of the lower limb has occurred quite often as a result of micro-angiopathy.<br /> <strong>Objective:</strong> This study aimed to investigate the bacterial spreading and related outcomes of treatment in 81 patients with diabetic foot complicated by infection.<br /> <strong>Materials and methods:</strong> A retrospective study based on the analysis of the patients medical records from the hospital database. The bacteriological analysis of the tissues from infected wounds, obtained during surgical debridement or amputation, were conducted in all patients. Microbiological investigations of the the contents of an aerobic and anaerobic bacterial flora in the wounds were compared and analyzed in all cases considered suitable for this study.<br /> <strong>Results:</strong> Analysis of microbial spreading revealed growth of bacteria in all diabetic foot wounds. Associations of aerobes with anaerobes were found in 89.9 % of the cases. Escherichia coli was the dominating agent among anaerobes (22%), leading to development of infectious process and distributed in a proximal direction along synovial-tendon sheets of the foot.<br /> <strong>Conclusion:</strong> Aggressive debridement of necrotized tissues, including proximal and distal parts of tendons up to 5 cm within the limits of healthy looking tissues may disrupt further spreading of purulent infection and lead to favorable outcome.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583735
- DOI -
- Views 106
- Downloads 0
Towards Precise Identification of The Medically Important Flesh Fly, Sarcophaga (Liopygia) argyrostoma (Robineau-Desvoidy, 1830) (Diptera: Sarcophagidae)
<span>Although of its medical importance and its role in the forensic investigation field, flesh fly, </span><span>Sarcophaga </span><span>(</span><span>Liopygia</span><span>) </span><span>argyrostoma </span><span>is not...
Polycythemia Vera (PV) Complicated by Late Diagnosis of Multiple Splenic Infarcts: A Case Report
Polycythemia vera (PV) is a chronic myeloproliferative tumor where bone marrow makes more red blood cells and other bone marrow cells. Many patients initially are asymptomatic, however, other patients may develop symptom...
The Role of Tonsillectomy in the Treatment of Obstructive Sleep Apnea
Background: Obstructive Sleep Apnea (OSA) is caused by a partial or complete obstruction of the upper airway. OSA is a very inconvenient and relatively common disorder with daytime and nocturnal symptoms. The interventio...
Fungemia in Immunocompromised Patients (Hematological Malignant and Hematopoietic Stem Cell Transplant Patients during Febrile Neutropenia)
<span>Background: </span><span>Fungal infections are a major cause of morbidity and mortality among febrile neutropenic patients.<br /> The choice of empiric antifungal regimen is based on susceptibility pattern of local...
Glucocorticoids Induced End Organs Damage in Patients with Systemic Lupus Erythematosus
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects multiple organs and requires long term treatment with GCs. GC-related end organ damage in SLE appears in the form of: osteoporo...