Bacterial Isolation And Antibiogram with Esbl Production of Klebiella Species From Exudates From Govt General Hospital ,Guntur.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Introduction: The number of organisms developing resistance to commonly used antibiotics is increasing among the various generations.Klebsiella species is associated with different types of infections and there is a preponderence of multidrug resistance and ESBL production. Materials and Methods : A total number of 2,240 exudate samples collected from March 2017 to October 2017 from Govt General hospital,Guntur were included in the study . Bacterial isolates were identified by their standard Microbiologicaltechniques and were subjected to antibiotic sensitivity testing using modified KirbyBauer disc diffusion method. RESULTS : Of 2,240 exudate samples processed ,746 (33.30%) samples were culture positive for various organisms.Itconisisted of 599 (80%) Gram negative bacteria. Of 746 culture ,368 (50%) were positive for Klebiella species,87 (11.76%) were Positive for Pseudomonas aueriginosa ,85(11.40%) were Escherichia coli, 51 (6.83 %) were Proteus species , 08 (2.17% ) were Citrobacter and 06(1.6% ) were acinetobacter . 95 (25.8%) were Staphylococcus aureus ,27( 7.33% ) were CONS and 19(5.16%) were Streptococci .The frequency of ESBL producers in our study was 72.5% of all Klebsiella isolates. Conclusion : Klebsiella species turns out to be the most frequently isolated organism with high ESBL prodution. Since the exact national scenario of antimicrobial resistance is not known in India owing to the absence of a central monitoring agency, we can asses the possible factors that can favour an antibiotic policy for the proper and effective use of antibiotics.
Authors and Affiliations
Dr. N. Subhalakshmi
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