Prediction of Fetal Asphyxia by Cord Blood Nucleated Red Blood Cell Counts
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Introduction: Birth asphyxia is a combination of hypoxia and hypoperfusion of the neonate during the intrapartum period leading to long term complications. Since blood gas analysis is not commonly available, search is on for a surrogate marker of fetal hypoxia which has high accuracy and at the same time is easy to measure and does not require specialised equipment. Materials and Methods: This prospective comparative study was conducted at tertiary care hospital in Rajasthan in 50 cases and 50 controls. Women with two or more of the parameters (Meconium staining of amniotic fluid, non-reassuring fetal heart rate patterns, Apgar score</=6 at 5 mins after birth and admission to NICU within 24hrs after birth) were included in the study group while women with none of these parameters were included in control group. Umbilical arterial pH and cord blood NRBC levels were measured at birth. Results: NRBC count in study group was 18.40(SD3.33) and in control group was 9.00(SD3.21). Significant association of elevated NRBC count was found with meconium staining of amniotic fluid, low Apgar scores, abnormal fetal heart rate patterns, admission to NICU within 24 hrs of birth and maternal tobacco use. Conclusion: NRBC count is a marker that can potentially be used for diagnosis of fetal hypoxia even in peripheral centres.
Authors and Affiliations
Dr. Sushruti Kaushal, Dr. Sunil Thakur, Dr. Shyam Bhandari, Dr. Tanu Priya
Keywords
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- EP ID EP439976
- DOI 10.9790/0853-1801104850.
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