Bacterial profiling of isolated MRSA strains from wounds in tertiary care hospital, Chennai, Tamil Nadu, India
Journal Title: Innovations in Pharmaceuticals and Pharmacotherapy (IPP) - Year 2015, Vol 3, Issue 2
Abstract
Staphylococcus aureus being the normal microflora of the body are much easily prone to become a vital wound pathogen as is easy to invade and colonise the broken skin that exposes an optimal environment for their growth when a wound occurs. As they are the most prevalent microbes in wound infections, indiscriminative use of antibiotics has increased the virulence and variations in resistance of these strains resulting in frequent occurrence of MRSA. This study thus aimed to scrutinise the incidence of MRSA in diverse wound infection types against their susceptibility pattern to different antibiotics. Microbes were profiled from the wound infections in 289 patients using various samples like pus, swab and tissue. From the isolated microbes, MRSA isolates was screened and antibiotic susceptibility testing using routine disk diffusion method was performed. The wound microbial profiling indicated incidence of Staphylococcus aureus (58.55 %) to be the predominant pathogen with an incidence of 40.44 % MRSA isolates. These isolates were susceptible to vancomycin, levofloxacin and amikacin. Routine screening for antibiotic susceptibility of MRSA strains is required to determine the effective antibiotic regime to be adopted in the hospital.
Authors and Affiliations
Ravichandran B
Keywords
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