Bacteriological profile and Antimicrobial resistance in Neonatal Septicemia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Septicemia remains significant cause of morbidity and mortality in the newborns, more so in the developing countries. Reports of multi resistant bacteria causing neonatal sepsis in developing countries are increasing. The prompt administration of the appropriate, efficient antibiotic to treat newborn infections would increase the number of lives saved. So this study will show predominant organisms causing septicemia and their antibiotic susceptibility testing. It was a retrospective study conducted in Department of Microbiology, Surat for April 2016 to September 2016. Samples received by department were included in the study. Blood culture samples were processed as per protocol and organisms were identified using standard biochemical tests. Antibiotic sensitivity was studied by Kirby-bauer disc diffusion method according to CLSI guidelines. A total of 56 isolates were identified out of 126 samples. Out of which Klebsiella pneumoniae was the most common followed by Enterococcus spp. and Coagulase Negative Staphylococcus. On sensitivity testing, >70% of gram negative bacilli isolates were sensitive to Ertapenem, Doripenem and Gatifloxacin whereas Methicillin resistance in gram positive cocci isolates was >75%. The present study shows the importance of periodic surveys for predominant organisms and sensitivity pattern responsible for neonatal septicemia. This will help in antibiotic policy of the institute.
Authors and Affiliations
Dr. Manali Shah, Dr. Geeta Vaghela, Dr. Summaiya Mullan
Keywords
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- EP ID EP249524
- DOI 10.9790/0853-1611101619
- Views 74
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