Bacteriological profile and resistance pattern of the microorganisms causing bacteremia with special emphasis on unusual blood isolates
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Bacteremia is a serious infection with high morbidity and mortality. Knowledge of the etiological agents of blood-stream infections and their antibiotic resistance pattern could help in the choice of empirical antibiotics. Aim: To determine the causative agents of blood stream infection along with their antibiotic resistance pattern in our hospital between 2013 and 2016 and also to identify the uncommon blood culture isolates. Materials and Method: A retrospective study that included isolates obtained from blood culture between January 2013 and December 2016. The identification and drug resistance pattern of the organisms were performed using standard microbiological techniques. For those patients whose blood yielded uncommon isolates, the medical records were looked into to identify the risk factors and outcome. Results: Of a total of 9,926 blood samples received for culture, 534 (5.38%) yielded positive results, of which 277 were Gram-positive organisms and 257 were Gram-negative organisms. The most common etiological agents of bacteremia in the present study were Coagulase Negative Staphylococcus species (37.27%) followed by Salmonella typhi (10.11%), Escherichia coli (9.36%) and Staphylococcus aureus (8.05%), of which 53.49% were MRSA. Conclusion: The most effective antibiotics against Gram positive organisms were vancomycin, teicoplanin and linezolid. The Gram negative organisms showed least resistance to antibiotics like amikacin, tobramycin and carbapenems. The uncommon isolates were all non-fermenting Gram negative bacilli and among these Burkholderia species and Stenotrophomonas maltophila were the most frequently isolated.
Authors and Affiliations
Preethi Venkatesan, Priyadarshini Shanmugam, Shameem Banu Abdul Satter
Keywords
Related Articles
- EP ID EP294685
- DOI 10.18231/2394-5478.2017.0036
- Views 82
- Downloads 0
Evaluation of risk factors and bacteriological profile of Neonatal Sepsis among patients admitted at Navodaya Medical College, Hospital and Research Center, Raichur
Introduction: Neonatal sepsis accounts for 69% of neonatal deaths in the developing world. Bacterial isolates and their antibiotic susceptibility has constantly been changing, which depends on several factors like gestat...
Evaluation of the Baseline Widal titre among apparently healthy individuals in Tumkuru, Karnataka, India
Background & Objectives: Enteric fever is a major public health problem in India. Widal test is a cheap, affordable and easily available and the most commonly used test for the serodiagnosis of enteric fever. The purpose...
Detection of Chlamydia Trachomatis infection among symptomatic women of reproductive age group attending the gynaecology OPD in a tertiary care centre and risk factors associated with the infection
Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection worldwide, affecting women more than men. Majority being asymptomatic, this infection goes unnoticed and will have a major impac...
Prevalence of multidrug resistant (MDR) Enterobacteriacae in rural tertiary care hospital
Multidrug resistant organisms (MDROs) infections have increased in recent years. The antibiotic resistance development in clinical isolates of Enterobacteriacae is rapid and that spread in the hospital. Objectives: 1)To...
Needle stick injury and health care workers: Scenario at GMC Akola, Maharashtra
Introduction: Needle stick injuries are the most common occupational hazard for health care workers as well as they carry the highest risk of transmission of various blood borne infections. The greatest menace are hepati...