BACTERIOLOGICAL PROFILE OF DIABETIC FOOT ULCERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 46
Abstract
BACKGROUND Diabetes mellitus is a progressive disease, diabetic foot is one of the major complications of diabetes mellitus and eventually leads to development of gangrene and lower extremity amputation. This study has been carried out to detect the antibiotic sensitivity pattern of the isolates in diabetic foot ulcer patients. MATERIALS AND METHODS This is a descriptive cross-sectional study. Pus and wound swabs were collected from around 100 diabetic patients with foot ulcer who attended the Surgery Out-Patient Department of Coimbatore Medical College Hospital. The samples received in the Department of Microbiology were processed for aerobic culture and antibiotic sensitivity testing during the study period. Blood samples were collected to analyse the HbA1c levels. RESULTS Of the 100 cases studied, most of the patients belonged to the 5th and 6th decades of life (37%) and (28%) respectively. Males were more affected compared to females with a ratio of 2.3:1. Maximum number of patients with Diabetic Foot Ulcers were seen in Wagner’s Grade II (40 nos.), followed by 38 DFI patients in Wagner’s Grade III. Among Gram positive aerobes, Staphylococcus aureus was the predominant isolate (18.4%). Among Gram negative aerobes, Proteus spp. was the most common isolate (23.2%) followed by E.coli 16.8% and Pseudomonas 16%. Acinetobacter species was the least common isolate (2.4%). While staphylococcus aureus was the most common among gram positive cocci, proteus was the most common isolate among the gramnegative pathogens. CONCLUSION Staphylococci and Proteus were the two most common isolates detected in diabetic foot infections. There was significant association between DFI and higher HbA1c levels. But no correlation was found between HbA1c levels and the polymicrobial nature of infection in DFI.
Authors and Affiliations
Shajahan Ansar, Ayesha Dastagir
Keywords
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- EP ID EP548054
- DOI 10.14260/jemds/2018/1112
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