Bacteriological Profile of Necrotising Fasciitis in A Teritary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Necrotising fasciitis is a potentially fatal infection that is rapidly progressive involving widespread necrosis of superficial fascia and subcutaneous tissue. It is usually associated with diabetes mellitus, trauma, Cirrhosis liver, chronic kidney disease, etc. The present study was conducted in the Department of Microbiology, Govt. Medical College, Thiruvananthapuram for a period of 1 year from May 2014 to April 2015. The objective of the study was to isolate and identify the bacterial pathogens causing Necrotising fasciitis from clinically diagnosed cases and to determine the Antibiotic susceptibility pattern of the isolates. A total number of 235 samples collected from the lesions of patients with necrotizing fasciitis admitted in the surgery wards during this period. Culture was positive in 222 samples (94.5%). Out of the total isolates, 96.5% were monomicrobial and 3.5% were poly microbial. The predominant isolate in the study was pseudomonas aeruginosa (37.44%) other isolates are Staphylococcus aureus (19.1%), Klebsiella species (11.91%), E.coli (7.65%), Streptococcus pyogenes (4.25%), Enterococci & Proteus vulgaris (3.4% each), Proteus mirabilis & CONS (2.97% each), MRSA (1.7%) and Enterobacter species (0.42%). The antibiotic sensitivity pattern of pseudomonas aeruginosa showed 100% sensitivity to Amikacin, Ceforazone – Sulbactum and Piperacillin tazobactam. Staphylococcus aureus isolates were sensitive to Cloxacilin, Amikacin and Vancomycin (100%). All the strains were resistant to penicillin. After treatment with appropriate antibiotics according to the antibiotic sensitivity pattern and surgical intervention, 204 (86.8%) patients survived. Mortality rate was 13.2% which was significantly reduced when compared to other studies because of the early treatment with appropriate antibiotics.
Authors and Affiliations
Dr Mariette Jane Pious
Keywords
Related Articles
- EP ID EP246324
- DOI -
- Views 80
- Downloads 0
Effects of Yogasanas in the Management of Pain during Menstruation
Menstrual irregularities are main problems in females due to many reasons. The aim of the study is to evaluate effects of yogasanas in the management of pain during menstruation.100 patients were selected as subjects, am...
A Cross sectional Study on role of MRI and its Clinico-Radiological correlation of Patients with White Matter Disease
Objectives: our study was to evaluate the clinico and radiological correlation and to find the role of MRI as an investigative modality for diagnosis of patients with white matter diseases. Methodology: A total of 30 cas...
Healthcare Today – Does it lack Empathy
Attention, Attention: Code blue, Code blue, fifth floor. As this strikes my ears, within less than a minute a group of highly trained professionals surface at the scene. One starts providing compressions, another takes t...
A Study of Refractive Errors in Pseudophakia
Background: Cataract is the most prevalent, treatable cause of visual impairment and blindness in the world. Cataract surgery with an intraocular lens (IOL) implant is one of the most common and thought to be the most ef...
Comparison of the Performance of QF-PCR with QPCR as A Rapid Molecular-Based Method for Sex Chromosome Aneuploidies Detection
Objective: The high prevalence and variable phenotype of sex chromosome aneuploidies, necessitated the development of a robust method allowing their rapid prenatal diagnosis. Quantitative Fluorescent Polymerase Chain Rea...