Basic mechanisms of antiepileptic drugs and their pharmacokinetic/pharmacodynamic interactions: an update.
Journal Title: Pharmacological Reports - Year 2011, Vol 63, Issue 2
Abstract
This article aims to summarize the current views of AED action and the promising new targets for the pharmacotherapy of epilepsy. In the first section of this paper, a neurobiological basis of epilepsy treatment and brief pharmacological characteristics of classical and new AEDs will be presented. In the second part, the results of experimental studies that have combined AEDs with similar or different mechanisms of action will be discussed.
Authors and Affiliations
Władysław Lasoń, Monika Dudra-Jastrzębska, Konrad Rejdak, Stanisław Czuczwar
Keywords
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