Behaviour of Uric Acid, the Final Metabolic Product of Purines, in Stored CPDA (Citrate-Phosphate-Dextrose-Adenine) Whole Blood Units
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 8
Abstract
Abstract:Some nutrient media like CPDA (Citrate -phosphate-dextrose-adenine), for blood storage, contain adenine for improved storage of erythrocytes, but the dynamics of its final catabolic product i.e. uric acid (UA) has not been studied in detail. Sixteen CPDA-1 whole blood bags were used for baseline and subsequent weekly determination of UA, Potassium (K), Sodium (Na) and Albumin (Alb) in the extracellular fluid and Hemoglobin (WB Hb) in whole blood during the initial four weeks of storage using automated machines. Unidirectional changes were seen in concentrations of K (increase; ANOVA p< 0.0001), Na (decrease; ANOVA p< 0.0001) whereas no change was seen in WB Hb (ANOVA p= 0.99) and a tri-modal pattern (increase-decrease-increase) was observed for UA (ANOVA p < 0.0001) and Alb (ANOVA p= 0.01) across the storage period. The changes in K and UA might prove useful in conferming the age of blood bags. Keywords:CPDA, Uric acid, Potassium, Sodium, Albumin, Hemoglobin
Authors and Affiliations
Simant Baliarsingh
Keywords
Related Articles
- EP ID EP373164
- DOI -
- Views 64
- Downloads 0
Comparative Study between Exteriorization of Uterus during Cesarean Section Versus Intraperitoneal or in-Situ Repair
The objectives of this study is to assess intraoperative and postoperative advantages and disadvantages following exteriorization of uterus as compared to those with intraperitoneal or in-situ repair and to assess intra...
Prelabour rupture of membranes at term: Expectant Management vs Induction of labour
Abstract: Prelabour rupture of membranes is defined as rupture of membranes before labour and occurs in 0.8% of all pregnancies at term. This study was conducted at Government Maternity hospital, Sultanbazar, Hyderabad f...
Lower urinary tract dysfunction symptoms by Modified Dysfunctional Voiding Scoring System in school age (6-12 years) children
Abstract: Main objective of the study was to identify lower urinary tract dysfunction (LUTD) symptoms in children aged 6-12 years by using Modified Dysfunctional Voiding Scoring System (DVSS) and the association of these...
Determination of Sexual Dimorphism in Bikaner city population in Rajasthan by Odontometric Study of Permanent Maxillary Canine
Abstract: Establishment of a person's individuality is important for legal as well as humanitarian purpose and gender determination is an essential step in identifying an individual. Dental, fingerprint and DNA compariso...
Ectopic Pregnancy: A Devastating Catastrophe
Abstract: Ectopic pregnancy is the most devastating catastrophe in early pregnancy. The clinical presentation of ectopic pregnancy has changed from a life-threatening disease, necessitating emergency surgery, to a benign...