Bell’s Palsy Treatment: Comparison of Famciclovir plus Prednisolone with Prednisolone Alone
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
Not many Indian studies have evaluated role of antiviral drug Famciclovir in treatment of Bell’s palsy. Aim of this study was to analyze and compare clinical and electrophysiological recovery with Famciclovir plus prednisolone and prednisolone alone in treatment of Bell’s palsy. 50 patients with clinical features compatible with Bell’s palsy were included in the study .Detailed clinical, laboratory and electrophysiological evaluations of patients were done and patients were randomized into two groups. Group I received Famciclovir plus prednisolone while the Group II received 10 days of oral prednisolone alone. Outcome was assessed at 3 months with House–Brackmann scale and the patients were followed up to a period of three months. The mean age of patients was 35.0 years with M: F ratio of 64: 36. No significant differences exist between the groups in terms of age and gender. The rate of complete recovery was 68% in group I and 60% in the group II (p=0.04). The results of this study showed that the combined prednisolone and famciclovir therapy of patients with Bell’s palsy is more effective than treatment with prednisolone alone.
Authors and Affiliations
Dhermendra Pratap Singh, Sandeep Aggarwal, Kameshwar Prasad
Keywords
Related Articles
- EP ID EP486540
- DOI -
- Views 71
- Downloads 0
A Study of Hospital Based Epidemiology, Role of Routine Biochemistry & Evaluation of Causes Underlying New Onset Seizures Presenting to the Emergency Department
Abstract: The patients who present to the emergency with seizures are usually in a state of altered sensorium or comatose and are not able to tell about the preceding events i.e. (aura progressing to seizure activity). H...
Misplaced IUCD: Etiology and Management-A Retrospective Study
Abstract: Intrauterine copper devices are considered as a highly effective, non-hormonal method ofcontraception that can be safely used by all women regardless of breastfeeding status during this interval. They can be in...
Expression of the Coxsackie-Adeno-Virus Receptor on Pancreatic β-Cells of Rat and Human Origin
Abstract: Type 1 diabetes mellitus is a disease that results from autoimmune destruction of the insulin-producing beta-cells in the pancreatic islets of Langerhans. This process is induced in genetically susceptible indi...
Pure Dislocation of Patella
We report in this work a rare case of dislocation of the right patella persistent until the reception of the patient in the emergency, shows the maneuver of reduction and its management in the emergency but especially it...
To Study and type the Ovarian Tumors based on Histopathological features
Abstract: Ovary is the most important organ, as it is concerned with the reproduction of progeny. Ovary is also unique in the variety of lesions that can arise from it. Ovarian cancer accounts for about 3% of all cancers...