Binomial Distribution Sample Confidence Intervals Estimation 7. Absolute Risk Reduction and ARR-like Expressions
Journal Title: Leonardo Electronic Journal of Practices and Technologies - Year 2004, Vol 3, Issue 5
Abstract
Assessments of a controlled clinical trial suppose to interpret some key parameters as the controlled event rate, experimental event date, relative risk, absolute risk reduction, relative risk reduction, number needed to treat when the effect of the treatment are dichotomous variables. Defined as the difference in the event rate between treatment and control groups, the absolute risk reduction is the parameter that allowed computing the number needed to treat. The absolute risk reduction is compute when the experimental treatment reduces the risk for an undesirable outcome/event. In medical literature when the absolute risk reduction is report with its confidence intervals, the method used is the asymptotic one, even if it is well know that may be inadequate. The aim of this paper is to introduce and assess nine methods of computing confidence intervals for absolute risk reduction and absolute risk reduction – like function.Computer implementations of the methods use the PHP language. Methods comparison uses the experimental errors, the standard deviations, and the deviation relative to the imposed significance level for specified sample sizes. Six methods of computing confidence intervals for absolute risk reduction and absolute risk reduction-like functions were assessed using random binomial variables and random sample sizes.The experiments shows that the ADAC, and ADAC1 methods obtains the best overall performance of computing confidence intervals for absolute risk reduction.
Authors and Affiliations
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
Keywords
Related Articles
- EP ID EP82507
- DOI -
- Views 114
- Downloads 0
Conjugate Gradient Method with Ritz Method for the Solution of Boundary Value Problems
In this paper, we wish to determine the optimal control of a one-variable boundary value problem using the Ritz algorithm. The posed optimal control problem was inadequate to achieve our goal using the Conjugate Gradient...
Development of a Light Dependent Automatic- Off Timer for House Holds Electronics
This work was undertaken to design and construct a device that would be of use to persons who are in the habit of falling asleep while watching or listening to music. The scope of work ranges from the conceptualization o...
Design, Construction and Testing of a Parabolic Solar Steam Generator
This paper reports the design, construction and testing of a parabolic dish solar steam generator. Using concentrating collector, heat from the sun is concentrated on a black absorber located at the focus point of the re...
Design and Construction of a Conical Screen Centrifugal Filter for Groundnut Oil Slurry
This work focuses on the design and construction of a conical screen centrifugal filter for the separation of groundnut oil slurry. The major component of the machine is the rotary conical screen which separates the pure...
Production and Characterisation of Zeolite from Ahako Clay in Kogi State, Nigeria
Zeolite, a multi-purpose material normally sourced from clay is usually for many Engineering applications. However, it is only those Zeolite that are technically well prepared that can give optimum performance during app...