Bioactive Compounds from Medicinal Plants and Their Importance in Drug Discovery in Pakistan
Journal Title: Matrix Science Pharma (MSP) - Year 2017, Vol 1, Issue 1
Abstract
Humans have relied on nature throughout their ages to cater for their basic needs including medicines to cure a wide spectrum of diseases. Plants have formed the basis for sophisticated systems of traditional medicines. For therapeutic agents many of the presently known lead compounds are natural products or their derivatives. Ethnomedicinal studies play a vital role to discover new drugs from indigenous medicinal plants. Green pharmaceuticals are getting popularity and extraordinary importance because vast opportunities for new drug discoveries are provided by the unmatched availability of chemical diversity and natural products either as pure compounds or as homogenous plant extracts. Therefore, in recent years the demand for herbal medicines and several natural products from a variety of plant species is consistently increasing. In spite of being an agricultural country and having different ecological regions, the medicinal plants of Pakistan have not been explored for their secondary metabolites which are responsible for treating different diseases. Although, huge importance of different extracts of medicinal plants from Pakistan have been reported for their different activities such as antimicrobial, anti-cancerouse, antiviral and antioxidant but complete biochemical profiling of these medicinal plants is lacking. LC-MS and GC-MS techniques have been applied in the field of drug discovery from medicinal plants but in Pakistan its success rate is very low in the subject of biochemical profiling. Therefore, such techniques should be used in Pakistan to explore active constituents from medicinal plants which could be used as medicines in future
Authors and Affiliations
Ghulam Mustafa, Rawaba Arif, Asia Atta, Sumaira Sharif, Amer Jamil
Keywords
Related Articles
- EP ID EP264152
- DOI 10.26480/msp.01.2017.17.26
- Views 147
- Downloads 0
RENAL CLEARANCE AND URINARY EXCRETION OF MOXIFLOXACIN IN HEALTHY MALE VOLUNTEERS
Moxifloxacin is a 4th generation fluoroquinolone. Study was planned on renal clearance and urinary excretion of moxifloxacin on healthy male volunteers by applying sensitive, rapid and accurate HPLC-UC analytical method....
The biochemical significances of the proximate, mineral and phytochemical composition of selected vegetables from Pakistan
Current study was designed to focus on the proximate, phytochemical and nutrient composition in addition to antioxidant properties of five selected vegetables viz Ipomoea batatas, Trigonella foenum-graecum, Daucus carota...
PHYTOCHEMICAL AND ANTIOXIDANT SCREENING OF CASSIA ANGUSTIFOLIA, CURCUMA ZEDOARIA, EMBELIA RIBES, PIPER NIGRUM, ROSA DAMASCENA, TERMINALIA BELERICA, TERMINALIA CHEBULA, ZINGIBER OFFICINALE AND THEIR EFFECT ON STOMACH AND LIVER
Herbal medicinal natural plants and species are mostly used for wide purposes in Pakistan in current situation. There are diverse variety of phytochemical constituents which are present in plants and act as secondary met...
Prevalence of Ectoparasitic Fauna and Ef�icacy of Two Commercial Acaricides against Argus persicus in Layer Poultry
Ectoparasites are responsible to transmit many bacterial and viral diseases in laying hens. A number of chemicals are used to manage tick infestation in laying birds. These include carbamates, avermectins, herbal product...
PHYTOCHEMICAL ANALYSIS ANDANTIBACTERIAL POTENTIAL OF LEAF EXTRACT OF BAUHINIA LINN.: AN ETHNOMEDICINAL PLANT
Various agents in medicinal plants are used in the same way as antibiotics in treatment of acquiring resistance in bacteria.The main objective of this study is to check out the bactericidal action of leaves of Bauhinia v...