Bioactive Principles in Two Polyherbal Traditional AntiDiabeteic Formulations
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5
Abstract
Bioactive principles in two polyherbal traditional anti diabetic formulations of different plants used in the treatment of diabetes mellitus mixed in different ratios were characterized using Infrared spectroscopy. Six medicinal plants with proven anti diabetic and related beneficial effects were selected for the preparation of two mixtures Acanthus montanus, Asystasia gangetica, Emilia coccinea, Hibiscus rosa-sinesis, Momordica charantia (Bitter melon), and Venonia amygdalina. Mixtures of the All- Six (AS) herbal leaves recorded these compounds 3-beta-acetoxy-5-etienic, acid dihydroxyacetone, acetobromo-alpha-D-galactose, dihydroxyacetone, ethylacetohydroxomate, P-tolyacetonitrile, 4-aminoacetophenone, dihydroxyacetone,ethylacetohydroxomate, ethyl-4-chloro-2-cyanoacetoacetate while mixtures of All-four (AF) herbal leaves recorded ethylacetohydroxamate, ethyl-4,4,4-trichloroacetate, 4 – amino – acetophenone, ethylacetohydroxamate, p – tolyacetonitrile, thiophene-2-acetonitrile, ethyl-4-chloro-2-cyanoacetoacetate, acetobromo-alpha-D-galactose, ethylacetohydroxamate, 4-aminoacetophenone and thiophene-2-acetonitrile. Functional groups such as those of the nitriles, benzene, acetals, cyano-compounds, amines, amides, substituted and conjugated ketones and aldehydes, alkaloids, phenyl groups, chlorocompounds, bromo sugar, glycosides, thiophene derivatives, amino substituted compounds and indoles were identified.
Authors and Affiliations
*Ogbuji C A. , 1, Ndulaka J. C. , Onuh, Emeka F, Eke Ugorji I.
Keywords
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- DOI 10.9790/3008-1205037583
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