Biochemical and histological study of traditional plant: Dodonaea viscosa Linn extracts in diabetic rats
Journal Title: The Journal of Phytopharmacology - Year 2013, Vol 2, Issue 4
Abstract
Aim of this study was to evaluate the individual biochemical changes of leaf extracts of Dodonaea viscose-A traditional plant in alloxan induced diabetic rats. Methanol and chloroform extract of Dodonaea viscosa were obtained by cold maceration and were administered to alloxan induced diabetic albino rats. Parameters including blood glucose, triglycerides, cholesterol, protein, urea, creatinine, SGPT, SGOT were checked using standard test kits and methods after administration of extracts. Histological changes in pancreas and liver of the animal were also examined. Extract treated groups shown reduction in blood glucose level to normal. Increased levels of all other biochemical parameters like SGPT, SGOT, Triglycerides, Cholesterol, Protein, Creatinine and Urea with alloxan treatment have been significantly reduced in extract treated groups. Histological changes supported this claim. Finally, the implications of results after administration of the extracts show their potential use in management of diabetes.
Authors and Affiliations
M. Sandhya Rani, P. Venkatesh, Dr. Rao. S. Pippalla, Dr. G. Krishna Mohan
Keywords
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