Biochemical and histological study of traditional plant: Dodonaea viscosa Linn extracts in diabetic rats
Journal Title: The Journal of Phytopharmacology - Year 2013, Vol 2, Issue 4
Abstract
Aim of this study was to evaluate the individual biochemical changes of leaf extracts of Dodonaea viscose-A traditional plant in alloxan induced diabetic rats. Methanol and chloroform extract of Dodonaea viscosa were obtained by cold maceration and were administered to alloxan induced diabetic albino rats. Parameters including blood glucose, triglycerides, cholesterol, protein, urea, creatinine, SGPT, SGOT were checked using standard test kits and methods after administration of extracts. Histological changes in pancreas and liver of the animal were also examined. Extract treated groups shown reduction in blood glucose level to normal. Increased levels of all other biochemical parameters like SGPT, SGOT, Triglycerides, Cholesterol, Protein, Creatinine and Urea with alloxan treatment have been significantly reduced in extract treated groups. Histological changes supported this claim. Finally, the implications of results after administration of the extracts show their potential use in management of diabetes.
Authors and Affiliations
M. Sandhya Rani, P. Venkatesh, Dr. Rao. S. Pippalla, Dr. G. Krishna Mohan
Keywords
Related Articles
- EP ID EP49520
- DOI -
- Views 245
- Downloads 0
Anxiolytic activity of ethanolic extract of aerial parts of Tribulus terrestris in mice
Herbs have always been a preferred choice of treatment for people of the subcontinent and the Indo-Pak subcontinent has a long tradition of the use of herbs as medicines. In the given study ethanolic extract of Tribulu...
Effect of aqueous extract of Talinum triangulae (water leave) in lead- induced chromosomal aberration
Phytomedicine is a subject that is now gaining relevance worldwide aiding treatment for diseases that were once incurable among folks in which genotoxicity is a prominent one. The present study was designed to examine...
Isolation of Daphnetin 8-methyl ether from Daphne oleoides and its Anti-bacterial activity
The aim of the present work was to isolate and identify secondary metabolites of Daphne oleoides, which was not phytochemically analysed in this important geographical region of the world until now, followed by the det...
Effect of kidney tonifying prescriptions- Liu wei di huang Wan and Ba wei di huang Wan on insulin resistance
Metabolic syndrome (MetS) is a cluster of symptoms seen in type 2 diabetes mellitus, cardiovascular diseases, hypertension and obesity. Insulin resistance is a major component of MetS and is thus the key to cure and pr...
Antidiabetic Herbal Drugs and Polyherbal Formulation Used For Diabetes: A Review
This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. It is caused by the deficiency or ineffective production of insulin by pancreas which results in increase or...