Isolation of Daphnetin 8-methyl ether from Daphne oleoides and its Anti-bacterial activity
Journal Title: The Journal of Phytopharmacology - Year 2015, Vol 4, Issue 4
Abstract
The aim of the present work was to isolate and identify secondary metabolites of Daphne oleoides, which was not phytochemically analysed in this important geographical region of the world until now, followed by the determination of anti-bacterial activity. An important plant coumarin daphnetin 8-methyl ether (1)[7-hydroxy- 8-methoxy coumarin] not previously reported from this species was isolated from the methanolic extract of aerial parts of Daphne oleoides, along with already reported 4-ethoxy benzoic acid (2)and 4-hydroxy benzoic acid(3) by repeated column chromatography. The structures of these compounds were elucidated on the basis of 1H, 13C NMR and MS analysis. The compound 1 was evaluated for its anti-bacterial potential which showed moderate activity.
Authors and Affiliations
Muhammad Younus Dar, Tabassum Ara, Seema Akbar
Keywords
Related Articles
- EP ID EP49644
- DOI -
- Views 194
- Downloads 0
Tinospora cordifolia Enhances Vyadhikshamatwa (immunity) in Children
Background: The immune system in children is constantly developing and they are at an increased risk of infections. It is vital to help enhance immunity by vaccination but more people are turning towards traditional me...
Ethnomedicinal survey of plants used by tribal in Lalgarh forest range, W.B., India
Exploration of the traditional knowledge of the indigenous people is very important for revealing the uses of plants and plant parts for medicinal purpose. Once the medicinal use of these plants is known, their active...
Effect of methanolic extract of Alchornea cordifolia leaves on the sexual behavior of senescent and sexually inexperienced rats
Alchornea cordifolia, a shrub found in tropical Africa, is used to treat several physiological disorders, including male infertility and impotency. The main objective of this study was to determine the effect of the me...
Evaluation of the fertility activity of the aqueous leaves extract of Zanthoxylum macrophylla (Rutaceae) on male rats
Zanthoxylum macrophylla, one of the useful medicinal plants in Cameroon, was scientifically conducted to find its aqueous extract leaves effect in some fertility parameters of male rats. 24 rats were randomly divided i...
A review of the plant Boerhaavia diffusa: its chemistry, pharmacology and therapeutical potential
Introduction: Boerhaavia diffusa, a perennial creeping weed found in tropics and sub-tropics is a well known ethno-medicinal plant. The whole plant as well as its different parts (leaves, roots and stems) and plant extr...