Biochemical, Anti-Diarrhoeal and Anti-Gastric Ulcer Activities of Commiphora myrrha
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 19, Issue 3
Abstract
Myrrh is a spiny, deciduous shrub or small tree growing about 5 meters tall. It usually has a small but distinct bole. An oleo-resin gum exudes from the bark of this species and various other members of the Commiphora genus, (Encyclopedia of Herbs and their Uses Bown. D. 1995, ISBN: 0-7513-020- 31, Dorling Kindersley, London) (Figure 1).The resin obtained from the bark of myrrh is a pungent, astringent, aromatic herb that is strongly stimulant, antiseptic and expectorant. Myrrh is used externally to treat mouth ulcers, wounds, boils, and is often added to oral preparations. An essential oil obtained from the resin is used by aroma-therapists as a natural antiseptic for treating skin and mouth problems. It was observed that there a significant difference in the Cmax, AUC, AUMC, t1/2 and MRT of theophylline when co-administered with Commiphora myrrha which indicate that the herb affects the metabolism and elimination when co-administered with theophylline [1]. Guggul gum resin from Commiphora wightii (syn. Commiphora mukul) has been used for centuries in Ayurveda to treat a variety of ailments [2]. The Commiphora resins possess anti-inflammatory and antitumor activity Antibacterial and antifungal bioassay shows antibacterial and antifungal activity higher in the myrrha oil than the Africana oil while antiviral bioassay shows higher antiviral activity in the Africana oil than myrrha oil [3]. Myrrh (“Morr” in Persian) is a yellow-brown aromatic oleo-gum resin obtained from the stems of the genus Commiphora, particularly C. myrrha (Burseraceae). It has been demonstrated that myrrh has broad spectrum of biological properties including antibacterial, antinociceptive, anti- inflammatory and anti-ulcer activities. Moreover, it has been reported that myrrh has antioxidant and immune potentiating properties [4].
Authors and Affiliations
Mohammad Kamil, Abdalla TM
Keywords
Related Articles
- EP ID EP621797
- DOI 10.26717/BJSTR.2019.19.003306
- Views 177
- Downloads 0
Late decrease of pCREB in the Basolateral Amygdala by Social Interaction Reward
Background: The transcription factor CREB (cAMP response element-binding protein) has been shown to be activated by drugs of abuse in reward-related brain regions. However, the effects of natural reward on CREB activatio...
Sentinel Ganglion
Sentinel lymph node technique is well known among physicians who treat breast cancer or melanoma but is roll in colorectal cancer is still under investigations. We made an analysis of this simple technique th...
Caecal Volvulus: An Uncommon Disease with Common Presentation
Caecal volvulus is rare cause of intestinal obstruction. However, it is imperative to know the predisposing factors to make an early diagnosis of cecal volvulus and would be able to decrease morbidity and mortality. Here...
Photochemical Mechanism for the Air Inflammation Propagation
It was found that transfer of air inflammation,from the,Electronically Energy Explosion (EEE) active zone into fresh (non-reacted) air mixture is produced by photochemical process including UV radiation of NO(B2П) molecu...
Thiolated DAB Dendrimer-Gold Nanoparticles Self-Assembled Monolayer as Covalent Support for Direct Electrochemistry of HRP and Sensing Applications
A thiolated DAB dendrimer has been employed to bond gold nanoparticles of several sizes in order to obtain an electrocatalytic framework for the covalent immobilization and direct electrochemistry of horseradish peroxida...