Biochemical, Anti-Diarrhoeal and Anti-Gastric Ulcer Activities of Commiphora myrrha
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 19, Issue 3
Abstract
Myrrh is a spiny, deciduous shrub or small tree growing about 5 meters tall. It usually has a small but distinct bole. An oleo-resin gum exudes from the bark of this species and various other members of the Commiphora genus, (Encyclopedia of Herbs and their Uses Bown. D. 1995, ISBN: 0-7513-020- 31, Dorling Kindersley, London) (Figure 1).The resin obtained from the bark of myrrh is a pungent, astringent, aromatic herb that is strongly stimulant, antiseptic and expectorant. Myrrh is used externally to treat mouth ulcers, wounds, boils, and is often added to oral preparations. An essential oil obtained from the resin is used by aroma-therapists as a natural antiseptic for treating skin and mouth problems. It was observed that there a significant difference in the Cmax, AUC, AUMC, t1/2 and MRT of theophylline when co-administered with Commiphora myrrha which indicate that the herb affects the metabolism and elimination when co-administered with theophylline [1]. Guggul gum resin from Commiphora wightii (syn. Commiphora mukul) has been used for centuries in Ayurveda to treat a variety of ailments [2]. The Commiphora resins possess anti-inflammatory and antitumor activity Antibacterial and antifungal bioassay shows antibacterial and antifungal activity higher in the myrrha oil than the Africana oil while antiviral bioassay shows higher antiviral activity in the Africana oil than myrrha oil [3]. Myrrh (“Morr” in Persian) is a yellow-brown aromatic oleo-gum resin obtained from the stems of the genus Commiphora, particularly C. myrrha (Burseraceae). It has been demonstrated that myrrh has broad spectrum of biological properties including antibacterial, antinociceptive, anti- inflammatory and anti-ulcer activities. Moreover, it has been reported that myrrh has antioxidant and immune potentiating properties [4].
Authors and Affiliations
Mohammad Kamil, Abdalla TM
Keywords
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- EP ID EP621797
- DOI 10.26717/BJSTR.2019.19.003306
- Views 157
- Downloads 0
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