Biochemical Changes in The Intervertebral Discs After Electromagnetic Radiation: An Experimental Study
Journal Title: Journal of Neurological Sciences-Turkish - Year 2012, Vol 29, Issue 1
Abstract
Objective: We investigated the intervertebral discs in a rat electromagnetic radiation (EMR) model to demonstrate that electromagnetic radiation is a cause of degenerative intervertebral discs. Methods: Rats were randomly divided into four groups: group I consisted of control rats, and groups II-IV comprised electromagnetically irradiated with 900, 1800 and 2400 MHz. The rats were placed into a specially designed mechanism, and their heads were exposed to 900, 1800 and 2400 MHz microwaves irradiation for 1 h per day for 2 months. The control group rats were placed into same system. The same procedure was applied to the control group while the rats were not exposed to the electromagnetic waves. Results: The intervertebral disc Interleukin-1β levels as well as the total antioxidative capacity (TAC) and total oxidative capacity (TOS) values in the EMR groups (900, 1800, 2400 MHz) were higher than those in the control group (p<0.05). In the EMR groups, group II intervertebral disc Interleukin-1β levels and TAC were not significantly different from those in group III (P>0.05). Group II intervertebral disc TOS was significantly different from that in groups III and IV (P<0.05). In the Oxidative Stress Index (OSI) comparisons , group II was significantly different from groups I, III and IV (P<0.05). Conclusions: Electromagnetic radiation increased the intervertebral disc release of inflammatory cytokine IL-1β and oxidative radicals. This process can lead to degeneration of intervertebral disc.
Authors and Affiliations
Olcay ESER, Ahmet SONGUR, Veli ÇAĞLAR, Huseyin VURAL, Ergun KARAVELİOGLU, Hakan MOLLAOGLU, Fehmi OZGUNER
Keywords
Related Articles
- EP ID EP93137
- DOI -
- Views 109
- Downloads 0
Chorea-Ballismus Associated With Nonketotic Hyperglycemia Without Hyperosmolality: A Case Report
A 77 years old diabetic voman presented with a sudden onset of generalized chorea-ballismus (CB). Laboratory screening revealed uncontrolled diabetes with absent ketones and normal serum osmolality. There were no any abn...
Bir Çocukta Serebral Glioblastoma Multiforme'nin Spinal Leptomeningeal Metastazı
Searbral glioblastoma multiformenin spinal metastatik yayılımı ve klinik bulgular vermesi nadirdir. 11 yaşında erkek hasta baş ağrısı ile başvurdu. Manyetik Rezonans Görüntüleme (MRG)’sinde sol lateral ventrikül oksipita...
Colloid Cyst in Cavum Septum Pellucidi: Rare Location and Endoscopic Removal
Colloid cysts are benign intracranial lesions, that account only 0.2-2% of intracranial lesions, mostly localized in the roof of the third ventricle. Although the cysts are histological benign, they sustain significant n...
Epilepsi Hastalarında Nöronal Nos(Nos1) Polimorfizmi: Pilot Çalışma
Amaç:Nöronal NOS(nNOS), beyinde nöronal nitrik oksid sentaz enzimi aracılığı ile L-argininden sentezlenir. Merkezi Sinir Sisteminde(MSS)sinaps plastisitesi, nörotransmiter salınımı, nöronların hasarı ve nöronların korunm...
Late Onset Poststroke Seizures
The most common cause of seizures is cerebrovascular disease in elderly population. Late onset seizures are not investigated as well as early onset seizures in patients with stroke. There is no common consensus about cli...