Biochemical Changes in The Intervertebral Discs After Electromagnetic Radiation: An Experimental Study
Journal Title: Journal of Neurological Sciences-Turkish - Year 2012, Vol 29, Issue 1
Abstract
Objective: We investigated the intervertebral discs in a rat electromagnetic radiation (EMR) model to demonstrate that electromagnetic radiation is a cause of degenerative intervertebral discs. Methods: Rats were randomly divided into four groups: group I consisted of control rats, and groups II-IV comprised electromagnetically irradiated with 900, 1800 and 2400 MHz. The rats were placed into a specially designed mechanism, and their heads were exposed to 900, 1800 and 2400 MHz microwaves irradiation for 1 h per day for 2 months. The control group rats were placed into same system. The same procedure was applied to the control group while the rats were not exposed to the electromagnetic waves. Results: The intervertebral disc Interleukin-1β levels as well as the total antioxidative capacity (TAC) and total oxidative capacity (TOS) values in the EMR groups (900, 1800, 2400 MHz) were higher than those in the control group (p<0.05). In the EMR groups, group II intervertebral disc Interleukin-1β levels and TAC were not significantly different from those in group III (P>0.05). Group II intervertebral disc TOS was significantly different from that in groups III and IV (P<0.05). In the Oxidative Stress Index (OSI) comparisons , group II was significantly different from groups I, III and IV (P<0.05). Conclusions: Electromagnetic radiation increased the intervertebral disc release of inflammatory cytokine IL-1β and oxidative radicals. This process can lead to degeneration of intervertebral disc.
Authors and Affiliations
Olcay ESER, Ahmet SONGUR, Veli ÇAĞLAR, Huseyin VURAL, Ergun KARAVELİOGLU, Hakan MOLLAOGLU, Fehmi OZGUNER
Keywords
Related Articles
- EP ID EP93137
- DOI -
- Views 99
- Downloads 0
Spraque-Dawley Ratlarda Paklitakselin Sinir İletim Hızı ve Motor Ünite Aksiyon Potansiyeline Etkileri
Bu çalışma paklitakselin erişkin erkek Spraque-Dawley ratlarında duyusal ve motor sinir iletim hızları (DSİH ve MSİH) ve motor ünite aksiyon potansiyelleri (MUAP) üzerine olan toksik etkilerini çalışmak için düzenlenmişt...
Superficial Siderosis Due To Third Ventricular Cavernous Malformation: Case Report
Cavernous malformations can be seen anywhere in the central nervous system. However their existence in intraventricular area is very rare. Superficial siderosis is an extensive deposit of hemosiderin the leptomeninges an...
Ulnar nerve entrapment neuropathy due to extraneural ganglia at the elbow: A case report
A rare case of ulnar nerve entrapment due to extraneural ganglion at the elbow is presented. A 64-year old right-handed man presented with a 6 months history of pain in his right elbow, progressive numbness, tingling, at...
Serebral sinüs trombozu
Behçet Hastalığı Olgularında Gastrokinemiyus H Refleks Yanıtı ve Sinir İletim Çalışması
Amaç: Bu çalışmada Behçet hastalığı (BH) olguları ile sağlıklı kontrollerin sinir iletim çalışması değerleri ve gastrokinemiyus H refleksi yanıtlarının karşılaştırılması amaçlanmıştır. Materyal ve Method: Ocak 2002 ve E...