Biochemical composition of the blood of cows with a serous mastitis
Journal Title: ВЕТЕРИНАРІЯ, ТЕХНОЛОГІЇ ТВАРИННИЦТВА ТА ПРИРОДОКОРИСТУВАННЯ - Year 2019, Vol 0, Issue 3
Abstract
Mastitis is one of the most significant and serious problems in dairy farming. This disease is still widespread throughout Ukraine among cows of different breeds. Currently, the understanding of only clinical, physiological and pathological indicators in diseases is not enough. It is also necessary to have data on biochemical changes in the body in any disease. It will help in deciphering the pathogenesis, detecting early diagnosis tests and testing the effectiveness of therapy methods. The purpose of our work was to study the dynamics of total protein and its fractions in the blood of clinically healthy and sick serous mastitis of cows using different methods of therapy for the further development of preventive measures of serous mastitis. The research was conducted in the farm of Sumy region in the summer-autumn and winter-spring periods of 2016-2018. For forming research groups of cows of the black-and-white breed with I and II calving with a diagnosis of serous mastitis are used, 15 animals of each were selected on the principle of analogues. A group of clinically healthy cows consisted of 10 animals. In the control group, a short novocaine blockade of the udder nerves was used according to D. Logvinov using 0.25% solution of novocaine at a dose of 150ml with the addition of 2 ml of hydrocortisone, three times, with an interval of 24 hours. In the first experimental group, an application was applied to the affected quarters of the udder of the emulsion, which included thiotriazolin, dimexide, menthol, anesthesin. The procedure was performed three times with an interval of 24 hours in combination with a light massage of the udder in the direction from the bottom up. In the second experimental group, a solution of 5 ml of thiotriazoline, 5 ml of 0.25% novocaine solution, 2 ml of dimexidum was injected into the affected quarter of the udder, three times, with an interval of 24 hours, in combination with a gentle massage of the udder. In the third experimental group, a complex treatment regime was used, which included thiotriazolin in a dose of 15 ml per cow in combination with the application of an emulsion consisting of dimexide, menthol, anesthesin, on the affected quarter of the udder, three times, with an interval of 24 hours. The content of total protein in serum was determined with biuret method, and protein fractions with electrophoresis. As a result of our research we determined that serous mastitis of cows is accompanied by a pronounced decrease in total protein in the blood due to a decrease in the albumin fraction, which is due to their easy penetration through the walls of blood vessels as a result of the inflammatory process, a significant increase in the fraction of α-globulins, which includes almost all proteins of the “acute phase”, and a tendency to a slight increase in the fractions of β- and γ-globulins, which shows at the intensification of immune processes in the body. The best effect of the treatment of cows with serous mastitis was observed in the control and III experimental groups, as evidenced by a change in biochemical parameters, in particular an increase in the level of total protein, albumin and γ-globulin, confirms the antiinflammatory, antihistamine, antioxidant, anesthetic, especially the immunostimulating effect drugs: thiotriazolin, novocaine, dimexidum and hydrocortisone.
Authors and Affiliations
Y. Baydevlyatova
Keywords
Related Articles
- EP ID EP576970
- DOI 10.31890/vttp.2019.03.03
- Views 214
- Downloads 0
Analysis of the efficacy of use hormone «Follimag» to stimulate reproductive capacity of female rabbit
In commercial rabbit meat production, the combination of artificial insemination and management in a batch system is widely used and has replaced natural mating. However, in such systems the success of AI depends l...
Моніторинг проблем та тенденцій розвитку галузі козівництва в Україні
У оглядовій статті наведено моніторинг основних проблем сучасного стану та розвитку козівництва в Україні, виявлено найбільш вагомі перешкоди у виробництві продукції на промисловій основі, визначено тенденції та запропон...
FORENSIC INSPECTION OF SOUL-MILK CHEESE ON MATERIALS CRIMINAL PROCEEDINGS
The materials of pre-trial investigation of criminal proceedings and materials of forensic inspection of sour-milk cheese on the fact of supplying this counterfeit product to budget educational institutions have been use...
STUDY OF THE IMPACT OF THE NEW METHYLTHEOPHYLLINE DERIVATIVE ON THE KIDNEYS FUNCTIONAL STATE OF THE RATS ON THE BACKGROUND OF SPONTANEOUS DIURESIS
The results concerning the impact of the new methyltheophylline derivative -7-benzoylmethyl-8-(furyl-2)-methylaminotheophylline on the activity of the kidneys in rats under conditions of spontaneous diuresis and figuring...
TUBERCULOSIS OF PHEASANTS AND PEAFOWLS: ASPECTS OF THANATOGENESIS
Recently, the issue of how to prevent spreading of bird tuberculosis draws more and more attention. Exotic bird species are often kept in zoo aviaries for many years and therefore can be a hidden infection source not onl...