Biofilm Formation and Antibiotic Susceptibility Profile of Uropathogens: A Study
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 1
Abstract
Introduction: Urinary tract infection (UTI) is one of the commonest causes of infections in humans. The causative organisms of UTI may be bacteria, fungi and viruses. 95% of UTI are caused by bacteria. The uropathogens commonly form biofilm causing persistence of infection. Aim: To study the biofilm formation and antibiotic susceptibility profile of uropathogens. Material & Methods: 200 bacterial strains isolated from urine samples were included in the study. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion method according to CLSI Guidelines. Biofilm formation was detected by Tube nmethod. Results: 77.5% strains were Gram negative bacilli and rest were Gram positive cocci. E.coli was the commonest isolate. All (100%) Gram positive cocci were resistant to Penicillin. 29% of Gram negative bacilli & 46.7% of Gram positive cocci were strong biofilm producers. Conclusion: The emperical treatment of UTI must be stopped. Antibiotic Susceptibility testing and detection of Biofilm producing strains for uropathogens should be done routinely.
Authors and Affiliations
Dr. Silpi Basak
Keywords
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