Evaluation of out of field dose and comparison of dose to healthy tissue between VMAT and IMRT plans.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 3
Abstract
Background: Purpose of this study was to evaluate out of field dose calculation accuracy against measured dose and comparing the dose to healthy tissue between VMAT and IMRT plans. Methods and materials: We created a plan with various field sizes to deliver 1Gy dose at 1.58cm in a homogeneous phantom. The calculated dose along the central axis at three depths 1.58cm, 5.0cm and 10.0cm was noted down. Calculated monitor unit was delivered and measured. Dose difference between calculated and measured was found. Ten patients with prostate cancer were selected to evaluate healthy tissue dose with VMAT and IMRT plans. Difference between VMAT and IMRT plans was compared statistically. Results: The deviation between calculated and measured was lesser than 1% within the field. From field edge to 5cm the maximum deviation was -36%, -28% and -15% at Dmax, 5cm and 10cm depths respectively among all points. For larger field size the percentage of error was larger. VMAT controlled the higher doses to healthy tissue within the treatment field along with low and intermediate doses to tissues out of the treatment field (p<0.002). Conclusion: Out of field dose calculation accuracy was reduced for larger field size. VMAT can control dose to healthy tissue volume and it can help to reduce secondary cancer risk.
Authors and Affiliations
Jayapalan Krishnan
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