Biohemical Parameter of Liver in Congestive Cardiac Failure

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Biohemical Parameter of Liver in Congestive Cardiac Failure

Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 10

Abstract

Introduction: Liver dysfunctions associated with heart failure are mild in nature and discovered accidently during routine biochemical investigations. The aim of the present study was to determine the importance of liver biochemical markers amongst patients of heart failure. Material and methods: The present prospective study was conducted in the Department of Biochemistry, Kakatiya Medical College and MGM Hospital, Warangal, Telangana, India during a period of one year. It was conducted from June 2016 to July 2017. The controls were age matched with the cases. Appropriate laboratory investigations were done to determine both direct and indirect total serum bilirubin. Serum aspartate and alanine aminotransferase, serum alkaline phosphatase levels were also estimated. Patient’s serum albumin, proteins and prothrombin time was also taken into consideration. All the results were arranged in a tabulated form and analysed using SPSS software. Results: There were a total of 60 subjects who were enrolled in the study. The mean age of the subjects was 34.56+/-4.32 years. The mean age of females was 32.45+/-3.44 years and males were 37.76 +/- 5.41 years. The total bilirubin level amongst cases was 1.84 +/-0.89 and controls were 0.85 +/- 0.74. The conjugated bilirubin level amongst cases was 0.20 +/-0.18 and controls were 0.05 +/-0.04. The unconjugated bilirubin level amongst cases was 1.61 +/-0.97 and controls were 0.83 +/-0.32. Conclusion: From the present study it is clearly evident that there is significant difference in the level of hepatic markers amongst patients of heart failure and controls.

Authors and Affiliations

Gonella Geetha Meenakshi

Keywords

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