Biological activities and phytochemical analysis of extracts Afrostyrax lepidophyllus Mildbr. seeds
Journal Title: The Journal of Phytopharmacology - Year 2017, Vol 6, Issue 2
Abstract
Oxidative stress, one of the causes of certain diseases, prompts the search for new antioxidant molecules to reduce or limit the damage caused by it. In this study, the antioxidant, anti-inflammatory and anti-xanthine oxidase activity of the extracts (cyclohexane, dichloromethane, ethyl acetate and methanol) of the Afrostyrax lepidophillus seeds used in the human diet and the Central African Pharmacopoeia Been measured. Total pholyphenols, flavonoids, tannins and anthocyanins were also quantified in this work .The IC50 (inhibitory concentration which reduces free radicals by 50%) of the antioxidant activity of their extracts are respectively of the order of 3890,5±4,3, 3313,8±3,5, 1872,8±1,0 et 248,4±0,1 mg/L. The phytochemical analysis of the various extracts (cyclohexane, dichloromethane, ethyl acetate and methanol) made it possible to quantify the polyphenol content of 13,1±0,4, 30,5±0,5, 51,8±1,6 et 33,2±4,0 mg eq AG/g Dry matter (MS). The tannin content is of the order of 2,35±0,3, 10,68±0,1, 7,78±0,2, mg eq Cat/g MS, That of anthocyanins is 0.79 ± 0.04, 0.65 ± 0.02, 1.65 ± 0.07 and 0.18 ± 0.03 mg eq C3GE / g MS. The analysis of the different correlations between the chemical families and the antioxidant activity showed that there is a weak correlation between the biological activity and the phenolic compounds.
Authors and Affiliations
Namkona Armel Frédéric, Bolevane Ouantinam Serge Florent, MOUSTAPHA Fatia, Worowounga Xavier, Ngaissona Paul, Koane Jean Noël, Syssa-Magalé Jean-Laurent
Evaluation of neuro-protective activity of Brihatvata Chinthamani Rasa
The objective of the study was to screen the neuroprotective role of Brihatvata Chinthamani Rasa, a compound mineral formulation extensively used in stroke condition in the Indian system of medicine. The selected anima...
Phytochemistry and proximate composition of root, stem bark, leaf and fruit of desert date, Balanites aegyptiaca
Balanites aegyptiaca or Desert date is a common plant in all dry lands of Africa and South Asia. Some parts of the plant are used as fish poisons but not poisonous to man. It is also used as medicine or food in humans...
A review of the plant Boerhaavia diffusa: its chemistry, pharmacology and therapeutical potential
Introduction: Boerhaavia diffusa, a perennial creeping weed found in tropics and sub-tropics is a well known ethno-medicinal plant. The whole plant as well as its different parts (leaves, roots and stems) and plant extr...
Gastric acid anti-secretory effects of aqueous leaf extract of Nauclea latifolia (Rubiaceae) in rats
The aqueous leaf extract of Nauclea latifolia has been shown to have anti-ulcer effect. Objectives: The present study was undertaken to investigate the effects of aqueous leaf extract of N. latifolia on gastric acid se...
Antioxidant and antidiabetic activity of Phoenix pusilla Gaertn. unripe fruit extract in streptozotocin-induced sprague dawley rats
The fruit of Phoenix pusilla Garetn. has been used in herbal medicines, as it is sweet, sour, cooling and laxative, cardiotonic, aphrodisiac, carminative and roborant. The objective of the present study was to investig...