BIOLOGICAL ACTIVITIES OF EXTRACTS AND SEASONAL VARIATION IN ESSENTIAL OIL COMPOSITION FROM MYRCIARIA GLAZIOVIANA (MYRTACEAE)
Journal Title: International Journal of Pharmacognosy - Year 2016, Vol 3, Issue 11
Abstract
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analysed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 - 806.15mg AA/g of extract), DPPH radical scavenging (IC50 = 9.77 - 14.06µg/mL) and lipid peroxidation inhibition activity (21.30 - 66.80 %). These data were correlated to the total phenolic content (270.19 - 351.01 mg GA/g of extract). The dichloromethanic extract of leaves exhibited the higher anticholinesterase potential (IC50 = 249.25µg/mL). Furthermore, the chemical composition of the essential oils from leaves collected in all seasons of the year was analysed by GC-MS and GC-FID. Only sesquiterpenes were identified in all essential oils and non-functionalized sesquiterpenes comprised the major fractions (from 66.8 to 79.3 %). An increase in non-functionalized compounds was observed in the warmer seasons. Germacrene B was the major compound in all seasons (from 26.8 to 30.1 %). In winter and autumn, high contents of germacrene D (10.2 and 10.0 %, respectively) and α-cadinol (12.1 and 12.0 %, respectively) were identified; germacrene D (14.0 %) was among the major compounds in summer and β-elemene (11.6 %), in spring.
Authors and Affiliations
Miriam Falkenberg et al.
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