Biological Activities of Talaromyces Purpurogenus T013
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 1
Abstract
In the study, Talaromyces purpurogenus T013, a filamentous fungi belonging to Talaromyces which was identified had been isolated from the high value Taxus baccata subsp. wallichiana. In order to find out a new source of antimicrobial and anticancer agents, T. purpurogenus cultured in YM was against five different kinds of pathogens including Salmonella typhi (16.77±0.21 mm), Pseudomonas aeruginosa (16.17±0.21 mm), Serratia marcescens (15.50±0.21 mm), Listeria monocytogenes (16.37±0.15 mm) and Vibrio parahaemolyticus (15.43±0.21 mm) by using the agar well diffusion method. There was cytotoxic ability on Hela cancer cell line at the concentration (100 mg/mL) by using sulforhodamin B assay. The chloroform fraction showed antimicrobial activities that suggested the purified agent with antimicrobial in this fraction will be obtained so far.
Authors and Affiliations
Tu Nguyen
Keywords
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