BIOLOGICAL IMPORTANCE OF QUINAZOLIN-4-ONE SCAFFOLD AND ITS DERIVATIVES–A BRIEF UPDATE
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 6
Abstract
Heterocyclic compounds form the basis of many pharmaceutical, agrochemical and veterinary products. Among a wide variety of nitrogen heterocyclic moieties that have been explored for developing pharmaceutically useful molecules, quinazolinone plays an important role in medicinal chemistry and subsequently have emerged as a pharmacophore that possess a diversity of useful biological activities. The pharmacodynamic versatility of quinazolin-4-one moiety has been documented not only in many of its synthetic derivatives but also in several naturally occurring alkaloids isolated from animals, plants and microorganisms. This review gives an overview update on some biological activities of the promising synthesized quinazolinone molecules.Â
Authors and Affiliations
B. Haseena Banu, K. V. S. R. G. Prasad, K. Bharathi
Keywords
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