BIOLOGICAL PROPERTIES OF THERMOSENSITIVE CHITOSAN GELS CONDITIONING IN WATER
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2015, Vol 0, Issue
Abstract
In this paper the properties of thermosensitive chitosan hydrogels prepared with the use of chitosan salz (chloride and lactate) and -glycerophosphate are presented. Biological studies were carried out on thermogels without conditioning in water and on thermogels after 24 h conditioning in water. Experiments were conducted on a reference cell line L 929 (NCTC clone 929) American Type Culture Collection according to Annex C PN-EN ISO 10993-5
Authors and Affiliations
Zofia Modrzejewska, Danuta Paluch, Agata Skwarczyńska
INFLUENCE OF CROSSLINKING PROCESS CONDITIONS ON MOLECULAR AND SUPERMOLECULAR STRUCTURE OF CHITOSAN HYDROGEL MEMBRANE
Unmodified (Ch) and ionically crosslinked with sodium tripolyphosphate (Ch/TPP) chitosan membranes were prepared. Various crosslinking conditions (pH, crosslinking time) were applied. Differences in membrane molecular st...
PLA MICROGRANULES USED AS CARRIERS OF ACTIVE SUBSTANCES PREPARED BY EMULSIFICATION IN CHITOSAN SOLUTION
The aim of research was the preparation of poly(lactide) and chitosan composite of spherical structures by emulsyfication of both polymers solutions. This resulted in fabrication of PLA microstructures (mPLA) suspended i...
VISCOMETRIC STUDIES OF MICROCRYSTALLINE CHITOSAN/POLY(VINYL ALCOHOL) MIXTURES
In the present paper, the results of viscosity measurements in dilute solutions of microcrystalline chitosan (MCCh) with poly(vinyl alcohol) (PVA) of different degrees of hydrolysis are presented. Microcrystalline chitos...
EFFECT OF A POLYVINYL ALCOHOL AND SELECTED AUXILIARY SUBSTANCES ON THE PROPERTIES OF THERMOSENSITIVE HYDROPHILIC GELS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN
Gels containing lactic acid complexed with chitosan at a stechiometric ratio 1:1 and 2:1 and 5-25% content of PEG-200 reveal pH from 3.42 to 4.95. The addition of 20 – 25% poloxamer 407 increases the pH from 4.55 to 5.30...
DEVELOPMENT OF MUCOADHESIVE CHITOSAN-BASED DRUG DELIVERY SYSTEM
Chitosan is a highly versatile biopolymer characterised by low toxicity, biocompatibility, and slow but complete biodegradation in the human body, possessing multiple reactive groups. One of the most well-known propertie...