Biosynthesis of silver nanoparticles using Streptomyces griseus PDS1 for anticancer activity

Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5

Abstract

Biological synthesis of nanoparticles provides advancement over chemical and physical methods. The use of micro-organisms to synthesize functional nanoparticle has been of great innovative interest. The research work focus on synthesis of silver nanoparticle using Streptomyces griseus PDS1. Both crude and filtered culture developed into nanoparticle. The reduction of silver ions was observed and monitored with the help of UV spectrum. Further an array of absorbance bands of silver nanoparticle was observed in FTIR. The size of the nanoparticle was observed under scanning electron microscope. The antimicrobial activity of produced nanoparticle was performed against the bacteria such as Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli and fungi Aspergillus niger. The development of cotton gauze with nanoparticle against Pseudomonas aeruginosa for anti cancer activity was recorded for biomedical application.

Authors and Affiliations

M. Suba Sri, M. Mekala, K. Suganya, B. Nandhini

Keywords

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  • EP ID EP392137
  • DOI 10.9790/3008-1206021116
  • Views 87
  • Downloads 0

How To Cite

M. Suba Sri, M. Mekala, K. Suganya, B. Nandhini (2017). Biosynthesis of silver nanoparticles using Streptomyces griseus PDS1 for anticancer activity. IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS), 12(5), 11-16. https://europub.co.uk/articles/-A-392137