bla NDM-1 GENE CARRIAGE IN THE ICU OF TERTIARY CARE HOSPITAL IN NORTH INDIA
Journal Title: IJSR-International Journal Of Scientific Research - Year 2019, Vol 8, Issue 2
Abstract
BACKGROUND:- New Delhi metallo-β-lactamase 1 (NDM-1) enzyme leads to multidrug resistance and has been detected from bacteria in many countries. The study was done To detect bacteria carrying blaNDM-1 gene from intensive care unit (ICU) patients and correlate the change with increasing duration of ICU stay. METHODS:- Blood and urine samples were collected from 140 patients thrice- 0-2 days, 3-7 days and 7 days of ICU admission. All bacterial isolates resistant to meropenem were evaluated for Metallo-β-lactamase (MBL) production. blaNDM-1 gene was detected using Real Time PCR from the MBL producers. RESULT:- Overall, 458 samples (229 each) of blood and urine were collected and 75 gram negative bacteria were isolated. From these, 46.7% (35/75) strains were found to be carbapenem resistant and blaNDM-1 gene was detected in 17.3% (13/75). CONCLUSION:- High prevalence of bacteria carrying blaNDM-1 gene was seen in ICU patients increasing the burden on healthcare.
Authors and Affiliations
Dr. Swati Sharma, Dr. Anuj Sud, Dr. Beena Uppal
Keywords
Related Articles
- EP ID EP463592
- DOI -
- Views 112
- Downloads 0
QUESTIONNAIRES BASED SURVEY ON COMPREHENSIVE KNOWLEDGE ABOUT ADRENAL DISORDER IN MEDICAL STUDENTS IN CENTRAL INDIA
BACKGROIND-India accounts for more than 1/5th of world”s tuberculosis cases.Post tubercular adrenalitis as adrenal insufficiency is one of commonest cause of cardiovascular instability leading to shock and death in India...
ABNORMAL UTERINE BLEEDING: CLINICOHISTOPATHOLOGICAL SPECTRUM AND CORRELATION
Background: Abnormal Uterine Bleeding (AUB) is considered one of the most common and challenging problems presenting to the gynecologists and accounts for as many as one third of all outpatients. Material and Methods: A...
STUDY OF EPIDEMIOLOGY OF HAND SURGERY CASES IN INDIAN SCENARIO
PURPOSE: - To study the epidemiology of hand surgery cases in Indian scenario. METHODS: - Retrospective study of hand surgery cases operated in the year 2015-2016 at a tertiary centre in India and the cases were further...
A COMPARITIVE STUDY OF SAFETY AND BENFITS IN BETWEEN LAPAROSCOPIC APPENDICECTOMY VERSUS OPEN APPENDICECTOMY.
The aim of this study is to compare the safety and benefits of laparoscopic versus open appendectomy in a prospective randomized study. Methods: Two hundred fifty patients were analyzed following either laparoscopic or o...
HYALINIZING CLEAR CELL CARCINOMA OF PALATAL MINOR SALIVARY GLAND: A CASE REPORT
Hyalinizing Clear Cell Carcinoma is a rare malignant neoplasm’s of salivary gland origin and accounts for 0.5% of all head and neck malignancies. Histological diagnosis of the tumour is challenging and needs to be differ...