Blood lactate levels and its association with survival outcome in polytrauma patients
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 8, Issue 3
Abstract
Background: Lactate as a marker for tissue hypoperfusion is an established biomarker for morbidity and mortality in patients with sepsis and trauma, but has limited clinical application. Aim of this study is was significant (P<0.001) as compared to 2.8 in survivor. The mean blood lactate level in non to evaluate serial serum lactate levels and its association with mortality of the patients of traumatic injury admitted in trauma centre. Many studies have confirmed relationship between tissue hypoxia and generation of lactate. Reflecting the level of tissue hypoxia, we examined the relationship between blood lactate level and survival rate. Materials and Methods: After the admission of patients of traumatic injury (n=63) in the trauma centre and the establishment of diagnosis, for the evaluation of serial blood lactate levels, we have collected the sample at the time of admission, 12 hours, 24 hours, and 36 hours subsequently. Comparison of two means between survivor and non survivor was performed using unpaired student t test. Results: Out of 63 patients 5 were non survivor and 58 were survivor. The mean blood lactate level in non-survivor was 5.9 at the time of admission, which -survivor was 2.7 after 36 hours, which was also significant (P<0.001) as compared to 0.98 among survivor. Conclusion: Blood lactate level at the time of admission and lactate clearance during the initial hours of admission can be a good predictor of patient’s morbidity and mortality. However, some of our patients with elevated initial lactate values recovered well, probably due to better treatment
Authors and Affiliations
Sunil Sureshbhai Patan, Maulik Nayak, Hitesh P Bariya
Keywords
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- EP ID EP442173
- DOI 10.26611/10028232
- Views 164
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