BLOOD LIPID PROFILE IN PRIMARY OPEN-ANGLE GLAUCOMA: A BIOCHEMICAL ANALYSIS STUDY
Journal Title: Kocatepe Medical Journal - Year 2021, Vol 6, Issue 22
Abstract
OBJECTIVE: Investigation of blood lipid profile in primary open-angle glaucoma (POAG). MATERIAL AND METHODS: In this study, there were 100 participants, of whom 50 were patients with POAG and 50 were non-POAG patients consulted in the ophthalmology clinic. Levels of blood lipids including total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglyceride (TG) were investigated. Data were compared with t-test, Mann Whitney U, Fischer correlation and Chi-square test. p<0.05 was considered statistically significant. RESULTS: While the mean age of the POAG patients was 65.7±11.09 years, the mean age of the non-POAG patients was 66.2±10.44 years. The normal reference ranges for laboratory tests in this study were 0-200 mg/dl for total cholesterol, 0-130 mg/dl for LDL, 35-70 mg/dl for HDL, and 35-160 mg/dl for TGs. The blood lipid levels in POAG and non-POAG patients were as following: total cholesterol 199±47 mg/dl and 202±46 mg/dl (p>0.05), LDL 114±37 mg/dl and 112±43 37 mg/dl (p>0.05), HDL 51±14 mg/dl and 54±19mg/dl (p>0.05), and TG 170±69 mg/dl and 146±102 mg/dl (p<0.05), respectively. CONCLUSIONS: In this study, no statistically significant difference was found between POAG and non-POAG patients regarding total cholesterol, LDL, and HDL levels. Yet, changes in the blood lipid profile may be associated with not only the patients' age but also prevalent systemic diseases. The present study demonstrated a remarkable finding that the level of TG was higher in the POAG patients compared to the general population.
Authors and Affiliations
Leyla ERYİĞİT EROĞUL, Murat KAŞIKÇI, Özgür EROĞUL, Hamidu Hamisi GÖBEKA
Keywords
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- EP ID EP697196
- DOI https://doi.org/10.18229/kocatepetip.772149
- Views 128
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