Blood stream infections with Candida species: a prospective study in a tertiary care center
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 12
Abstract
Candidemia describes the presence of Candidaspecies in the blood [1,2]. Invasive Candidiasis embodies a variety of diseases including Candidemia, dissemi¬nated Candidiasis, meningitis, and endo-phthalmitis. Most common form of invasive Candidiasis is Candidemia. Candidemia is a life-threatening affliction in most of the patients. Invasive Candidiasis has been of a concern as there is increased length and cost of hospitalizations as well as morbidities/ mortalities of patients [1,3,4,5].Currently Candidemia is the 4th most common etiological agent nosocomial bloodstream infections [6,7]. Certain ICU populations, especially HIV and burn victims, are at even higher risk for Candida infection than is the typical ICU patient. Hence, Candida in a blood culture should never be viewed as a contaminant and should always prompt a search for the source of the bloodstream infection. In the last 2 decades a change in the epidemiology of Candidemia has been noticed across the world [8,9,10,11,12]. With the change in the spectrum of Candida species causing Candidemia incidence of antifungal resistance of those yeasts are also on rise. With a high mortality rate of 35–75 % early antifungal treatment is essential for survival [13,14,15] Objectives of Our Study- The primary objective: Incidence of bloodstream infections with Candida species among the total number of positive bloodstream infections in a tertiary care hospital in Kerala over a period of 1.5 year. Secondary objective is to study distribution of Candidemia with respect to characteristics like age, gender, comorbid illness, mechanical ventilation, prior antibiotic therapy, prolonged ICU stay, indwelling device, to study current pattern of antifungal susceptibility and to determine the outcome, in terms of ICU admission and mortality.
Authors and Affiliations
Arun Divakar, M. Gopala Krishna Pillai, Anil Kumar V, Rithesh Reddy
Keywords
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- EP ID EP277654
- DOI 10.17511/ijmrr. 2017.i12.07
- Views 131
- Downloads 0
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