Bone Marrow Aspiration Cytology Study in a Tertiary Care Center, Gujarat, India
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 10
Abstract
Background: Hematological disorders are quite frequent in all age groups. Bone marrow aspiration (BMA) is crucial in evaluation, diagnosis, and management of anemia and other hematological disorders, especially in situation where diagnosis remains cryptic after detailed clinical history, physical examination, and peripheral blood analysis. This relatively safe and simple procedure is important particularly in resource-poor center since assess to adjuvant diagnostic techniques is often lacking. The present study aims to analyze the causes of hematological disorders, its spectrum, and indication of BMA findings. Materials and Methods: This was a retrospective as well as prospective study carried out in the Department of Pathology, Government Medical College and Sir Takhtasinhji Hospital, Bhavnagar, Gujarat, India, over 3 years 6 months. BMA of 141 cases was carried out and examined by the expert. Patient details regarding clinical history, physical examination, and laboratory reports were retrieved. Results: Of 141 patients, total of 28 cases were excluded from the study due to inadequate material or dry tap. Majority of the patient were of pediatric age group (<15 years). Male-to-female ratio was 1.17:1. The most frequent indication for BMA was unexplained anemia (44.24%) and thrombocytopenia (19.46%), followed by pancytopenia (16.18%) and suspected leukemia (9.73%). 7.96% BMA was absolutely normal without any pathology. Nutritional anemia (52.21%) was the most common pathological finding, followed by immune thrombocytopenia (11.5%), leukemia (8.84%), and aplastic anemia (6.19%). Conclusion: BMA cytology is a relatively simple, safe, and cheap yet a highly informative and important diagnostic test of wide range of hematological disorders in developing country like India.
Authors and Affiliations
Mayuri Gohil, Kruti Rathod
Keywords
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