Bone Marrow Cell Therapy in Complex Fistula-In-ANO
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
Perianal fistula is a worldwide health problem that can affect any person anywhere. Complex perianal fistula is a fistula which has multiple tract, horse shoe tract, suprasphincteric extension or a recurrent fistula & fistula associated with crohn’s disease, ulcerative colitis, tuberculosis etc. Surgical management of this type of fistula is not free from risk ; often result in recurrence and high risk of fecal in continence if an extensive surgical debridement is performed. The post operative complication like pain, tenderness, discharge, incontinence, recurrence are more common. In our study we have tried the autologous bone marrow therapy to operative site to prevent such complication. Two group of patient were selected randomly having complex fistula in ano; containing 20 patient in each group. The patient are under contrast group were treated by conventional fistulectomy alone ; where study group were treated by fistulectomy followed by autologous bone marrow cell therapy to operative site. The patient follow up. The post operative pain in control group 9 (45%) but in study nil recurrence. Tenderness persist. 8 (45%) in contrast group; but in study group 2 (10%) and require analgesic. HPE of granulation tissue from floor of ulcer at POD 7 shows more neovascularisation, more no. of fibroblast with inflammatory cell per high power field with minimal necrosis seen in 10 (80%) of study group and (20%) in control group. No incontinence in both group.
Authors and Affiliations
Prangya Lochan Chand
Keywords
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