Bone Marrow Examination in Cases of Pancytopenia
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 5
Abstract
Background: Pancytopenia is a relatively common hematological entity. This study was undertaken to find out the various causes of pancytopenia by bone marrow examination Methods: This was a retrospective study carried out to identify the causes of pancytopenia based on bone marrow examination. Bone marrow examinations were performed in 98 cases for indications over a period of one year , fulfilled the criteria of pancytopenia. Results: Total 98 cases of pancytopenia were examined during period of one year. The commonest cause of pancytopenia was megaloblastic anemia (33%) followed by aplastic/hypoplastic anemia (31%). other cause includes acute leukemia, myelodysplastic syndrome (MDS) and myelofibrosis.Conclusions: Bone marrow aspiration coupled with trephine biopsy can diagnosed majority cases of pancytopenia.Megaloblastic anemia and aplastic anemia are the commonest causes of pancytopenia. A comprehensive clinical and hematological study of patients with pancytopenia will help in the identification of Underlying cause.
Authors and Affiliations
Dr. Sakunthala, Dr. S. SUBITHA
Keywords
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