Bone Mineral status in newly Diagnosed Hyperthyroid Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Hyperthyroidism is a common disorder affecting a large group of population and is a cause of the osteoporosis. Bone homeostasis abnormalities in patients with hyper thyroidism causes alteration in serum calcium and phosphorous levels. The aim of the present study is to evaluate the levels of bone minerals like calcium and phosphorous in newly diagnosed hyperthyroid subjects and controls. Total T3, T4, TSH, serum calcium and phosphorous levels were estimated. BMI was also measured for both controls and hyperthyroid patients. Total T3, T4, serum calcium and phosphorous levels have been found to be significantly higher where as TSH and BMI have been found to be significantly lower in hyper thyroid patients when compared to controls. Serum calcium and phosphorous levels elevated in hyperthyroidism patients. Elevated T3,T4 levels in hyperthyroidism causes the osteoclast formation by stimulating nuclear receptors leading to bone resorption, which results in high serum calcium levels by moving calcium from bone. Excessive tissue catabolism and decreased renal phosphate excretion causes increase in phosphorous levels.
Authors and Affiliations
Dr Vijayalakshmi. Ravella
Keywords
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