Borderline Ovarian Tumor—An Overview and Evidence Based Management
Journal Title: Pan Asian Journal of Obstetrics & Gynecology - Year 2019, Vol 2, Issue 1
Abstract
Borderline ovarian tumors are the epithelial neoplasm which need to be differentiated from ovarian carcinomas as there presentation and management differs from the latter. The important differentiating feature on histopathological examination is the absence of stromal invasion. In the spectrum of aggressiveness between epithelial ovarian carcinoma and benign ovarian tumors such as cystadenoma, borderline tumors are closer to benign ovarian tumors in their clinical behavior. Surgery with intention of removal of all visible tumors is the mainstay of the treatment. Low recurrence rate for patients treated conservatively with fertility sparing surgery and good results with laparoscopic surgery makes them viable options as per the circumstances. Overall prognosis of these tumors is good with survival rate more than 90% at 10 years in early stage borderline tumors but small fraction of patients with borderline tumors may exhibit more aggressive course, and attempts have been made to identify histological correlates that might predict for worse outcome. There is no added advantage of postoperative adjuvant chemotherapy or radiation in any stage especially with non invasive component. Observation is the mainstay of follow-up and any further intervention is kept reserved for recurrent disease. The aim of this article is to discuss the current literature regarding epidemiology, pathology, diagnosis, prognosis, recurrence trend and management recommendations with emphasis on areas of controversies and future prospects.
Authors and Affiliations
Roshan Perween, Tamkin Khan
Keywords
Related Articles
- EP ID EP611483
- DOI -
- Views 81
- Downloads 0
Type-2 Mayer-Rokitansky-Kuster-Hauser Syndrome with Periureteric Fibrosis: A Rare Association
Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, Type 2 is a form of mullerian agenesis typically associated with renal, skeletal, and ovarian abnormalities. It has an incidence of 1 in 1,00,000 in general population. Thi...
Do It Yourself Abortion Pills”: Current Scenario in India
Background: Despite liberalization and legalization of abortion in India, over the counter sale and self-administration of abortion pills or do it yourself practice has shown rapid increase which at times may endanger th...
Luteal Phase Support: Why, When and How
Luteal phase support (LPS) is a known intervention for preventing the pregnancy loss. It is most commonly used in the artificial reproduction cycles. Most common agent used for the LPS is progesterone. Current review dis...
Bladder Pain Syndrome—Current Concepts and Management Guidelines
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic debilitating condition with increasing incidence globally. Despite of regular update of guidelines by different regulatory bodies still there is a lack of...
Pigmentation after Iron Polymaltose Infusion: Learning Points
A 40 year multiparous female presented with menorrhagia and severe anemia. She had been diagnosed as a case of fibroid uterus with menorrhagia with iron deficiency anemia. She received 1000 mg of iron polymaltose complex...