Brain natriuretic peptide: Potential adjunct for cardiac risk assessment and management during treatment with experimental anticancer agents
Journal Title: The AAPS Journal - Year 2007, Vol 9, Issue 2
Abstract
Authors and Affiliations
Mary L. Varterasian, Mark B. Meyer, Milton L. Pressler, Howard J. Fingert, Patricia M. LoRusso
Development of a Population Pharmacokinetic Model for Taranabant, a Cannibinoid-1 Receptor Inverse Agonist
Taranabant is a cannabinoid-1 receptor inverse agonist developed for the treatment of obesity. A population model was constructed to facilitate the estimation of pharmacokinetic parameters and to identify the influence o...
Pediatric Biopharmaceutical Classification System: Using Age-Appropriate Initial Gastric Volume
The online version of this article (doi:10.1208/s12248-016-9885-2) contains supplementary material, which is available to authorized users.
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ADME of Antibody–Maytansinoid Conjugates
The concept of treating cancer with antibody-drug conjugates (ADCs) has gained momentum with the favorable activity and safety of trastuzumab emtansine (T-DM1), SAR3419, and lorvotuzumab mertansine (IMGN901). All three A...
The Coulter Principle for Analysis of Subvisible Particles in Protein Formulations
The Coulter principle can be used for analysis of subvisible particles in protein formulations. The approach has several advantages including: an orthogonal operating principle, high sensitivity, ability to detect very s...