Breast Cancer Vaccine – Prioritizing Deterrence
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2015, Vol 3, Issue 3
Abstract
The control of the immune system through the administration of avaccine to direct a successful and enduring immune response against breast cancer cells is an alluring method. Vaccine would have a few hypothetical preferences over standard therapy, including low toxicities, high specificity, and long lasting efficacy because of the establishment of immunological memory. On the other hand, Breast Cancer vaccines have failed to exhibit significant results in clinical trials as such. This reflects the inborn trouble in breaking the complex immune escaping mechanism created by tumor cells. New vaccine ought to have the capacity to evoke complex immunologic reaction including numerous immune effectors, for example, Cytotoxic and antibody secreting B cells, innate immunity effectors, and memory cells. In addition, particularly in patients with large tumor burdens and metastatic disease, combining vaccines with different procedures, for example, systemic Breast cancer treatments, passive immunotherapy, or immunomodulatory agents could expand the viability of each methodology.
Authors and Affiliations
Col (Dr) Surinder Kumar Yadav| Head of Department, Dept. of Public Health, Amity Medical School, Amity University, Gurgaon, India., Pramod Singh Khatri| Assistant Professor and Programme Coordinator, Dept. of Clinical Research, Amity Medical School, Amity University, Gurgaon, India.
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