BUCCAL DRUG DELIVERY SYSTEM: THE CURRENT INTEREST
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 12
Abstract
This review highlights the several advantages of buccal drug delivery system (BDDS) over the conventional and systemic formulation majorly. It helps to enhance bioavailability through bypassing the first pass metabolism. On this drug delivery system the formulation keeps in contact with the mucosal surface resulting in better absorption and prolonged resident time. Though all drugs are not suitable for this drug delivery system yet is useful for most of the drugs. Bioadhesive polymers roles a major part in this drug delivery system because the extent of Mucoadhesion is a very important phenomena for the buccal drug delivery system. This review covers merits and demerits of buccal drug delivery system, anatomy of oral mucosa, mechanism of drug permeation, polymers and permeation enhancer used in buccal drug delivery system. This review also covers available marketed product as buccal drug delivery system and future aspects of buccal drug delivery system.
Authors and Affiliations
Mitul Patel , Asif Karigar , Pratik Savaliya , MV Ramana , Ashwini Dubal
Keywords
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