C - REACTIVE PROTEIN: AN INFLAMMATORY BIOMARKER PRESENT IN MULTIPLE DISEASE PATHOGENESIS
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 10
Abstract
C-reactive protein (CRP) is an acute-phase protein belongs to pentraxins family with a feature of ve identical globular subunits. Two different isoforms i.e. pentameric CRP (pCRP) and monomeric CRP (mCRP) have different key role in regulation. The key biological function of CRP is host defense using classical complement pathway against bacterial infection and involved in removal of apoptotic and necrotic cells. Although CRP is mainly associated with inammation in bacterial infection such as tuberculosis or Pneumococcus infection, however it is also presence in atherosclerosis, cardiovascular disease (CVD) and in various cancers which make it good candidate for prognostic study in different clinical conditions.
Authors and Affiliations
Parvinder Kaur, Ikram Qureshi, Prashant Khadke
Keywords
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